Tolanophane Revisited – Resolution and Racemization Mechanism of a Twisted Chiral Aromatic Compound

DOI Web Site Web Site Research Data 5 Citations 33 References

Search this article

Description

<jats:title>Abstract</jats:title><jats:p>Enantiomers of tolanophane consisting of two tolane units were resolved by chiral HPLC, contrary to the previous attempts by Staab et al. Racemization took place rapidly at room temperature, and the barrier to enantiomerization was determined to be 93.2 kJ mol<jats:sup>–1</jats:sup> at 283 K. This energy barrier was rationally deduced with a mechanism involving rotations about the single and triple bond axes, as revealed by DFT calculations. A tetrahedrane intermediate resulting from a transannular reaction between the two adjacent triple bonds was ruled out.</jats:p>

Journal

Citations (5)*help

See more

References(33)*help

See more

Related Data

See more

Related Projects

See more

Keywords

Details 詳細情報について

Report a problem

Back to top