Double Functionalization of Styrenes by Cu‐Mediated Assisted Tandem Catalysis

DOI Web Site Web Site Web Site 2 Citations 66 References
  • Daichi Kawauchi
    Graduate School of Pharmacuetical Sciences Tohoku University Aoba 6‐3, Aramaki, Aoba‐ku 980‐8578 Sendai, Miyagi Japan
  • Hirofumi Ueda
    Graduate School of Pharmacuetical Sciences Tohoku University Aoba 6‐3, Aramaki, Aoba‐ku 980‐8578 Sendai, Miyagi Japan
  • Hidetoshi Tokuyama
    Graduate School of Pharmacuetical Sciences Tohoku University Aoba 6‐3, Aramaki, Aoba‐ku 980‐8578 Sendai, Miyagi Japan

Description

<jats:p>The double functionalization of styrenes through Cu‐mediated assisted tandem catalysis was developed. The reaction was initiated by Cu‐catalyzed aziridination and the subsequent nucleophilic ring‐opening, which was triggered by the addition of (NH<jats:sub>4</jats:sub>)<jats:sub>2</jats:sub>S<jats:sub>2</jats:sub>O<jats:sub>8</jats:sub> as an oxidant of Cu‐catalyst to form a variety of C–C and C–X bonds. The expansion to three contiguous catalytic cycles led to the synthesis of functionalized indolines by one‐pot operation.</jats:p>

Journal

Citations (2)*help

See more

References(66)*help

See more

Related Projects

See more

Keywords

Report a problem

Back to top