Circulating levels of maternal plasma cell‐free miR‐21 are associated with maternal body mass index and neonatal birth weight

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  • Kiyonori Miura
    Department of Obstetrics and Gynecology Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan
  • Ai Higashijima
    Department of Obstetrics and Gynecology Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan
  • Yuri Hasegawa
    Department of Obstetrics and Gynecology Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan
  • Shuhei Abe
    Department of Obstetrics and Gynecology Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan
  • Shoko Miura
    Department of Obstetrics and Gynecology Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan
  • Masanori Kaneuchi
    Department of Obstetrics and Gynecology Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan
  • Koh‐ichiro Yoshiura
    Department of Human Genetics Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan
  • Hideaki Masuzaki
    Department of Obstetrics and Gynecology Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan

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<jats:p>What's already known about this topic? <jats:list list-type="bullet"> <jats:list-item><jats:p>Circulating cell‐free microRNA levels in maternal plasma are measurable.</jats:p></jats:list-item> <jats:list-item><jats:p>Circulating levels of some microRNAs are associated with pregnancy‐associated disorders.</jats:p></jats:list-item></jats:list></jats:p><jats:p>What does this study add? <jats:list list-type="bullet"> <jats:list-item><jats:p>Cell‐free miR‐21 levels in maternal plasma are independent of fetal gender.</jats:p></jats:list-item> <jats:list-item><jats:p>Neonatal birth weight affects plasma cell‐free miR‐21 levels.</jats:p></jats:list-item> <jats:list-item><jats:p>Maternal body mass index affects plasma cell‐free miR‐21 levels.</jats:p></jats:list-item></jats:list></jats:p>

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