Speed of sound in diseased liver observed by scanning acoustic microscopy with 80 MHz and 250 MHz
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- So Irie
- Chiba University 1 Graduate School of Engineering, , 1-33 Yayoicho, Inage, Chiba, Japan
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- Kenta Inoue
- Chiba University 1 Graduate School of Engineering, , 1-33 Yayoicho, Inage, Chiba, Japan
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- Kenji Yoshida
- Chiba University 2 Center for Frontier Medical Engineering, , 1-33 Yayoicho, Inage, Chiba, Japan
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- Jonathan Mamou
- Riverside Research 3 Lizzi Center for Biomedical Engineering, , 156 William Street, New York, New York 10038, USA
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- Kazuto Kobayashi
- Honda Electronics Co., Ltd. 4 , 20 Koyamazuka, Oiwa-cho, Toyohashi, Japan
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- Hitoshi Maruyama
- Chiba University Graduate School of Medicine 5 Department of Gastroenterology and Nephrology, , 1-8-1 Inohana, Chuo, Chiba, Japan
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- Tadashi Yamaguchi
- Chiba University 2 Center for Frontier Medical Engineering, , 1-33 Yayoicho, Inage, Chiba, Japan
説明
<jats:p>In this study, the speed of sound (SOS) of two types of rat livers (eight normal livers, four cirrhotic livers) was measured with a scanning acoustic microscope using two transducers, one of which had an 80-MHz and the other a 250-MHz center frequency. The 250-MHz transducer had a better spatial resolution adapted to studying fiber or hepatic parenchymal cells. In normal livers, averages of the SOS values were from 1598 to 1677 m/s at 80-MHz and from 1568 to 1668 m/s at 250-MHz. In the fiber tissue of cirrhotic livers, averages of the SOS values were from 1645 to 1658 m/s at 80-MHz and from 1610 to 1695 m/s at 250-MHz, while the SOS values in the other tissue of cirrhotic livers ranged from 1644 to 1709 m/s at 80-MHz and from 1641 to 1715 m/s at 250-MHz. In one liver, SOS in fiber tissue was larger than that of tissues without fiber while in others it was lower. The resulting two-dimensional SOS maps provide a unique quantitative insight of liver acoustic microstructures in a healthy liver and in a cirrhotic ones. This study would be helpful to understand the complex relationship between acoustic properties and liver disease including fiber tissue.</jats:p>
収録刊行物
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- The Journal of the Acoustical Society of America
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The Journal of the Acoustical Society of America 139 (1), 512-519, 2016-01-01
Acoustical Society of America (ASA)
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詳細情報 詳細情報について
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- CRID
- 1360567185883155712
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- ISSN
- 15208524
- 00014966
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- データソース種別
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- Crossref
- KAKEN