Patient-derived organoids can predict response to chemotherapy in metastatic colorectal cancer patients
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- Salo N. Ooft
- Department of Molecular Oncology and Immunology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
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- Fleur Weeber
- Department of Molecular Oncology and Immunology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
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- Krijn K. Dijkstra
- Department of Molecular Oncology and Immunology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
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- Chelsea M. McLean
- Department of Molecular Oncology and Immunology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
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- Sovann Kaing
- Department of Molecular Oncology and Immunology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
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- Erik van Werkhoven
- Department of Biometrics, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
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- Luuk Schipper
- Department of Molecular Oncology and Immunology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
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- Louisa Hoes
- Department of Molecular Oncology and Immunology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
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- Daniel J. Vis
- Oncode Institute, 3521 AL Utrecht, Netherlands.
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- Joris van de Haar
- Department of Molecular Oncology and Immunology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
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- Warner Prevoo
- Department of Radiology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
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- Petur Snaebjornsson
- Department of Pathology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
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- Daphne van der Velden
- Department of Molecular Oncology and Immunology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
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- Michelle Klein
- Department of Molecular Oncology and Immunology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
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- Myriam Chalabi
- Department of Molecular Oncology and Immunology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
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- Henk Boot
- Department of Gastrointestinal Oncology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
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- Monique van Leerdam
- Department of Gastrointestinal Oncology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
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- Haiko J. Bloemendal
- Department of Internal Medicine/Oncology, Radboud University Medical Center Nijmegen, 6525 GA Nijmegen, Netherlands.
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- Laurens V. Beerepoot
- Department of Internal Medicine, Elisabeth-TweeSteden Hospital, 5042 AD Tilburg, Netherlands.
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- Lodewyk Wessels
- Oncode Institute, 3521 AL Utrecht, Netherlands.
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- Edwin Cuppen
- Oncode Institute, 3521 AL Utrecht, Netherlands.
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- Hans Clevers
- Oncode Institute, 3521 AL Utrecht, Netherlands.
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- Emile E. Voest
- Department of Molecular Oncology and Immunology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
説明
<jats:p>Tumor organoids from individual patients with metastatic colorectal cancer can help predict response to irinotecan with or without 5-fluorouracil.</jats:p>
収録刊行物
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- Science Translational Medicine
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Science Translational Medicine 11 (513), eaay2574-, 2019-10-09
American Association for the Advancement of Science (AAAS)
