Optimization of a Series of Mu Opioid Receptor (MOR) Agonists with High G Protein Signaling Bias

  • Nicole M. Kennedy
    Department of Chemistry, The Scripps Research Institute, Jupiter, Florida 33458, United States
  • Cullen L. Schmid
    Department of Molecular Medicine, The Scripps Research Institute, Jupiter, Florida 33458, United States
  • Nicolette C. Ross
    Department of Chemistry, The Scripps Research Institute, Jupiter, Florida 33458, United States
  • Kimberly M. Lovell
    Department of Chemistry, The Scripps Research Institute, Jupiter, Florida 33458, United States
  • Zhizhou Yue
    Department of Chemistry, The Scripps Research Institute, Jupiter, Florida 33458, United States
  • Yen Ting Chen
    Department of Chemistry, The Scripps Research Institute, Jupiter, Florida 33458, United States
  • Michael D. Cameron
    Department of Molecular Medicine, The Scripps Research Institute, Jupiter, Florida 33458, United States
  • Laura M. Bohn
    Department of Molecular Medicine, The Scripps Research Institute, Jupiter, Florida 33458, United States
  • Thomas D. Bannister
    Department of Chemistry, The Scripps Research Institute, Jupiter, Florida 33458, United States

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