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- Swetansu K. Hota
- Gladstone Institute of Cardiovascular Disease 1 , San Francisco, CA 94158 , USA
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- Benoit G. Bruneau
- Gladstone Institute of Cardiovascular Disease 1 , San Francisco, CA 94158 , USA
書誌事項
- 公開日
- 2016-08-15
- 権利情報
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- http://www.biologists.com/user-licence-1-1
- DOI
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- 10.1242/dev.128892
- 公開者
- The Company of Biologists
この論文をさがす
説明
<jats:p>Precise gene expression ensures proper stem and progenitor cell differentiation, lineage commitment and organogenesis during mammalian development. ATP-dependent chromatin-remodeling complexes utilize the energy from ATP hydrolysis to reorganize chromatin and, hence, regulate gene expression. These complexes contain diverse subunits that together provide a multitude of functions, from early embryogenesis through cell differentiation and development into various adult tissues. Here, we review the functions of chromatin remodelers and their different subunits during mammalian development. We discuss the mechanisms by which chromatin remodelers function and highlight their specificities during mammalian cell differentiation and organogenesis.</jats:p>
収録刊行物
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- Development
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Development 143 (16), 2882-2897, 2016-08-15
The Company of Biologists
