Simple Behavioral Assessment of Mouse Olfaction

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<jats:title>Abstract</jats:title><jats:p>This unit presents two basic protocols that offer rapid assessments of anosmia (the absence of a sense of smell) in mice. The buried food test is used to check for the ability to smell volatile odors. The olfactory habituation/dishabituation test is used to test whether the animal can detect and differentiate different odors, including both nonsocial and social odors. A non‐contact method of odor presentation, along with a general method for collecting urine samples, is given as an alternate protocol. The tests described in this unit only require simple equipment and can be adopted readily by most laboratories.<jats:italic>Curr. Protoc. Neurosci</jats:italic>. 48:8.24.1‐8.24.12. © 2009 by John Wiley & Sons, Inc.</jats:p>

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