Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

Evangelos Evangelou, Helen R. Warren, David Mosen-Ansorena, Borbala Mifsud, Raha Pazoki, He Gao, Georgios Ntritsos, Niki Dimou, Claudia P. Cabrera, Ibrahim Karaman, Fu Liang Ng, Marina Evangelou, Katarzyna Witkowska, Evan Tzanis, Jacklyn N. Hellwege, Ayush Giri, Digna R. Velez Edwards, Yan V. Sun, Kelly Cho, J. Michael Gaziano, Peter W. F. Wilson, Philip S. Tsao, Csaba P. Kovesdy, Tonu Esko, Reedik Mägi, Lili Milani, Peter Almgren, Thibaud Boutin, Stéphanie Debette, Jun Ding, Franco Giulianini, Elizabeth G. Holliday, Anne U. Jackson, Ruifang Li-Gao, Wei-Yu Lin, Jian’an Luan, Massimo Mangino, Christopher Oldmeadow, Bram Peter Prins, Yong Qian, Muralidharan Sargurupremraj, Nabi Shah, Praveen Surendran, Sébastien Thériault, Niek Verweij, Sara M. Willems, Jing-Hua Zhao, Philippe Amouyel, John Connell, Renée de Mutsert, Alex S. F. Doney, Martin Farrall, Cristina Menni, Andrew D. Morris, Raymond Noordam, Guillaume Paré, Neil R. Poulter, Denis C. Shields, Alice Stanton, Simon Thom, Gonçalo Abecasis, Najaf Amin, Dan E. Arking, Kristin L. Ayers, Caterina M. Barbieri, Chiara Batini, Joshua C. Bis, Tineka Blake, Murielle Bochud, Michael Boehnke, Eric Boerwinkle, Dorret I. Boomsma, Erwin P. Bottinger, Peter S. Braund, Marco Brumat, Archie Campbell, Harry Campbell, Aravinda Chakravarti, John C. Chambers, Ganesh Chauhan, Marina Ciullo, Massimiliano Cocca, Francis Collins, Heather J. Cordell, Gail Davies, Martin H. de Borst, Eco J. de Geus, Ian J. Deary, Joris Deelen, Fabiola Del Greco M., Cumhur Yusuf Demirkale, Marcus Dörr, Georg B. Ehret, Roberto Elosua, Stefan Enroth, A. Mesut Erzurumluoglu, Teresa Ferreira, Mattias Frånberg, Oscar H. Franco, Ilaria Gandin, Paolo Gasparini, Vilmantas Giedraitis, Christian Gieger, Giorgia Girotto, Anuj Goel, Alan J. Gow, Vilmundur Gudnason, Xiuqing Guo, Ulf Gyllensten, Anders Hamsten, Tamara B. Harris, Sarah E. Harris, Catharina A. Hartman, Aki S. Havulinna, Andrew A. Hicks, Edith Hofer, Albert Hofman, Jouke-Jan Hottenga, Jennifer E. Huffman, Shih-Jen Hwang, Erik Ingelsson, Alan James, Rick Jansen, Marjo-Riitta Jarvelin, Roby Joehanes, Åsa Johansson, Andrew D. Johnson, Peter K. Joshi, Pekka Jousilahti, J. Wouter Jukema, Antti Jula, Mika Kähönen, Sekar Kathiresan, Bernard D. Keavney, Kay-Tee Khaw, Paul Knekt, Joanne Knight, Ivana Kolcic, Jaspal S. Kooner, Seppo Koskinen, Kati Kristiansson, Zoltan Kutalik, Maris Laan, Marty Larson, Lenore J. Launer, Benjamin Lehne, Terho Lehtimäki, David C. M. Liewald, Li Lin, Lars Lind, Cecilia M. Lindgren, YongMei Liu, Ruth J. F. Loos, Lorna M. Lopez, Yingchang Lu, Leo-Pekka Lyytikäinen, Anubha Mahajan, Chrysovalanto Mamasoula, Jaume Marrugat, Jonathan Marten, Yuri Milaneschi, Anna Morgan, Andrew P. Morris, Alanna C. Morrison, Peter J. Munson, Mike A. Nalls, Priyanka Nandakumar, Christopher P. Nelson, Teemu Niiranen, Ilja M. Nolte, Teresa Nutile, Albertine J. Oldehinkel, Ben A. Oostra, Paul F. O’Reilly, Elin Org, Sandosh Padmanabhan, Walter Palmas, Aarno Palotie, Alison Pattie, Brenda W. J. H. Penninx, Markus Perola, Annette Peters, Ozren Polasek, Peter P. Pramstaller, Quang Tri Nguyen, Olli T. Raitakari, Meixia Ren, Rainer Rettig, Kenneth Rice, Paul M. Ridker, Janina S. Ried, Harriëtte Riese, Samuli Ripatti, Antonietta Robino, Lynda M. Rose, Jerome I. Rotter, Igor Rudan, Daniela Ruggiero, Yasaman Saba, Cinzia F. Sala, Veikko Salomaa, Nilesh J. Samani, Antti-Pekka Sarin, Reinhold Schmidt, Helena Schmidt, Nick Shrine, David Siscovick, Albert V. Smith, Harold Snieder, Siim Sõber, Rossella Sorice, John M. Starr, David J. Stott, David P. Strachan, Rona J. Strawbridge, Johan Sundström, Morris A. Swertz, Kent D. Taylor, Alexander Teumer, Martin D. Tobin, Maciej Tomaszewski, Daniela Toniolo, Michela Traglia, Stella Trompet, Jaakko Tuomilehto, Christophe Tzourio, André G. Uitterlinden, Ahmad Vaez, Peter J. van der Most, Cornelia M. van Duijn, Anne-Claire Vergnaud, Germaine C. Verwoert, Veronique Vitart, Uwe Völker, Peter Vollenweider, Dragana Vuckovic, Hugh Watkins, Sarah H. Wild, Gonneke Willemsen, James F. Wilson, Alan F. Wright, Jie Yao, Tatijana Zemunik, Weihua Zhang, John R. Attia, Adam S. Butterworth, Daniel I. Chasman, David Conen, Francesco Cucca, John Danesh, Caroline Hayward, Joanna M. M. Howson, Markku Laakso, Edward G. Lakatta, Claudia Langenberg, Olle Melander, Dennis O. Mook-Kanamori, Colin N. A. Palmer, Lorenz Risch, Robert A. Scott, Rodney J. Scott, Peter Sever, Tim D. Spector, Pim van der Harst, Nicholas J. Wareham, Eleftheria Zeggini, Daniel Levy, Patricia B. Munroe, Christopher Newton-Cheh, Morris J. Brown, Andres Metspalu, Adriana M. Hung, Christopher J. O’Donnell, Todd L. Edwards, Bruce M. Psaty, Ioanna Tzoulaki, Michael R. Barnes, Louise V. Wain, Paul Elliott, Mark J. Caulfield

doi:10.1038/s41588-018-0205-x

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

DOI PDF Web Site 10 Citations

Evangelos Evangelou
Helen R. Warren
David Mosen-Ansorena
Borbala Mifsud
Raha Pazoki
He Gao
Georgios Ntritsos
Niki Dimou
Claudia P. Cabrera
Ibrahim Karaman
Fu Liang Ng
Marina Evangelou
Katarzyna Witkowska
Evan Tzanis
Jacklyn N. Hellwege
Ayush Giri
Digna R. Velez Edwards
Yan V. Sun
Kelly Cho
J. Michael Gaziano
Peter W. F. Wilson
Philip S. Tsao
Csaba P. Kovesdy
Tonu Esko
Reedik Mägi
Lili Milani
Peter Almgren
Thibaud Boutin
Stéphanie Debette
Jun Ding
Franco Giulianini
Elizabeth G. Holliday
Anne U. Jackson
Ruifang Li-Gao
Wei-Yu Lin
Jian’an Luan
Massimo Mangino
Christopher Oldmeadow
Bram Peter Prins
Yong Qian
Muralidharan Sargurupremraj
Nabi Shah
Praveen Surendran
Sébastien Thériault
Niek Verweij
Sara M. Willems
Jing-Hua Zhao
Philippe Amouyel
John Connell
Renée de Mutsert
Alex S. F. Doney
Martin Farrall
Cristina Menni
Andrew D. Morris
Raymond Noordam
Guillaume Paré
Neil R. Poulter
Denis C. Shields
Alice Stanton
Simon Thom
Gonçalo Abecasis
Najaf Amin
Dan E. Arking
Kristin L. Ayers
Caterina M. Barbieri
Chiara Batini
Joshua C. Bis
Tineka Blake
Murielle Bochud
Michael Boehnke
Eric Boerwinkle
Dorret I. Boomsma
Erwin P. Bottinger
Peter S. Braund
Marco Brumat
Archie Campbell
Harry Campbell
Aravinda Chakravarti
John C. Chambers
Ganesh Chauhan
Marina Ciullo
Massimiliano Cocca
Francis Collins
Heather J. Cordell
Gail Davies
Martin H. de Borst
Eco J. de Geus
Ian J. Deary
Joris Deelen
Fabiola Del Greco M.
Cumhur Yusuf Demirkale
Marcus Dörr
Georg B. Ehret
Roberto Elosua
Stefan Enroth
A. Mesut Erzurumluoglu
Teresa Ferreira
Mattias Frånberg
Oscar H. Franco
Ilaria Gandin
Paolo Gasparini
Vilmantas Giedraitis
Christian Gieger
Giorgia Girotto
Anuj Goel
Alan J. Gow
Vilmundur Gudnason
Xiuqing Guo
Ulf Gyllensten
Anders Hamsten
Tamara B. Harris
Sarah E. Harris
Catharina A. Hartman
Aki S. Havulinna
Andrew A. Hicks
Edith Hofer
Albert Hofman
Jouke-Jan Hottenga
Jennifer E. Huffman
Shih-Jen Hwang
Erik Ingelsson
Alan James
Rick Jansen
Marjo-Riitta Jarvelin
Roby Joehanes
Åsa Johansson
Andrew D. Johnson
Peter K. Joshi
Pekka Jousilahti
J. Wouter Jukema
Antti Jula
Mika Kähönen
Sekar Kathiresan
Bernard D. Keavney
Kay-Tee Khaw
Paul Knekt
Joanne Knight
Ivana Kolcic
Jaspal S. Kooner
Seppo Koskinen
Kati Kristiansson
Zoltan Kutalik
Maris Laan
Marty Larson
Lenore J. Launer
Benjamin Lehne
Terho Lehtimäki
David C. M. Liewald
Li Lin
Lars Lind
Cecilia M. Lindgren
YongMei Liu
Ruth J. F. Loos
Lorna M. Lopez
Yingchang Lu
Leo-Pekka Lyytikäinen
Anubha Mahajan
Chrysovalanto Mamasoula
Jaume Marrugat
Jonathan Marten
Yuri Milaneschi
Anna Morgan
Andrew P. Morris
Alanna C. Morrison
Peter J. Munson
Mike A. Nalls
Priyanka Nandakumar
Christopher P. Nelson
Teemu Niiranen
Ilja M. Nolte
Teresa Nutile
Albertine J. Oldehinkel
Ben A. Oostra
Paul F. O’Reilly
Elin Org
Sandosh Padmanabhan
Walter Palmas
Aarno Palotie
Alison Pattie
Brenda W. J. H. Penninx
Markus Perola
Annette Peters
Ozren Polasek
Peter P. Pramstaller
Quang Tri Nguyen
Olli T. Raitakari
Meixia Ren
Rainer Rettig
Kenneth Rice
Paul M. Ridker
Janina S. Ried
Harriëtte Riese
Samuli Ripatti
Antonietta Robino
Lynda M. Rose
Jerome I. Rotter
Igor Rudan
Daniela Ruggiero
Yasaman Saba
Cinzia F. Sala
Veikko Salomaa
Nilesh J. Samani
Antti-Pekka Sarin
Reinhold Schmidt
Helena Schmidt
Nick Shrine
David Siscovick
Albert V. Smith
Harold Snieder
Siim Sõber
Rossella Sorice
John M. Starr
David J. Stott
David P. Strachan
Rona J. Strawbridge
Johan Sundström
Morris A. Swertz
Kent D. Taylor
Alexander Teumer
Martin D. Tobin
Maciej Tomaszewski
Daniela Toniolo
Michela Traglia
Stella Trompet
Jaakko Tuomilehto
Christophe Tzourio
André G. Uitterlinden
Ahmad Vaez
Peter J. van der Most
Cornelia M. van Duijn
Anne-Claire Vergnaud
Germaine C. Verwoert
Veronique Vitart
Uwe Völker
Peter Vollenweider
Dragana Vuckovic
Hugh Watkins
Sarah H. Wild
Gonneke Willemsen
James F. Wilson
Alan F. Wright
Jie Yao
Tatijana Zemunik
Weihua Zhang
John R. Attia
Adam S. Butterworth
Daniel I. Chasman
David Conen
Francesco Cucca
John Danesh
Caroline Hayward
Joanna M. M. Howson
Markku Laakso
Edward G. Lakatta
Claudia Langenberg
Olle Melander
Dennis O. Mook-Kanamori
Colin N. A. Palmer
Lorenz Risch
Robert A. Scott
Rodney J. Scott
Peter Sever
Tim D. Spector
Pim van der Harst
Nicholas J. Wareham
Eleftheria Zeggini
Daniel Levy
Patricia B. Munroe
Christopher Newton-Cheh
Morris J. Brown
Andres Metspalu
Adriana M. Hung
Christopher J. O’Donnell
Todd L. Edwards
Bruce M. Psaty
Ioanna Tzoulaki
Michael R. Barnes
Louise V. Wain
Paul Elliott
Mark J. Caulfield

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Nature Genetics

Nature Genetics 50 (10), 1412-1425, 2018-09-17

Springer Science and Business Media LLC

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Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

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