<scp>C</scp>hina type 2 diabetes treatment status survey of treatment pattern of oral drugs users
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- Linong Ji
- Department of Endocrinology Peking University People's Hospital Beijing China
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- Juming Lu
- Department of Endocrinology Chinese PLA General Hospital Beijing China
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- Jianping Weng
- Department of Endocrinology The Third Affiliated Hospital of Sun Yat‐sen University Guangzhou China
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- Weiping Jia
- Department of Endocrinology Shanghai 6th Hospital Shanghai China
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- Haoming Tian
- Department of Endocrinology West China Hospital Chengdu China
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- Dalong Zhu
- Department of Endocrinology Nanjing Drum Tower Hospital Nanjing China
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- Xiaoping Xing
- Department of Endocrinology Peking Union Medical College Hospital Beijing China
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- Lixin Guo
- Department of Endocrinology Beijing Hospital Beijing China
Bibliographic Information
- Other Title
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- 对中国2型糖尿病患者口服降糖药物治疗模式的现状调查
Description
<jats:title>Abstract</jats:title><jats:sec><jats:title>Background</jats:title><jats:p>The aim of the present study was to investigate the current status of oral anti‐diabetic drug (<jats:styled-content style="fixed-case">OAD</jats:styled-content>) therapy in patients with type 2 diabetes and influencing factors in a real‐world setting in <jats:styled-content style="fixed-case">C</jats:styled-content>hina.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>A total of 9872 outpatients with type 2 diabetes, who had received <jats:styled-content style="fixed-case">OADs</jats:styled-content> (monotherapy or combination therapy) for at least 3 months were recruited in this study. Current antidiabetic treatment regimen and related clinical data were collected from medical records and analyzed.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>The most common <jats:styled-content style="fixed-case">OADs</jats:styled-content> in use were insulin secretagogues (70.2%) such as sulfonylureas (<jats:styled-content style="fixed-case">SUs</jats:styled-content>; 42.7%) or glinides (27.5%), followed by metformin (53.7%), α‐glucosidase inhibitors (35.9%), thiazolidinediones (17.2%), and dipeptidyl peptidase‐4 (<jats:styled-content style="fixed-case">DPP</jats:styled-content>‐4) inhibitors (0.8%). Dual‐drug combination therapy was more common (45.4%) than monotherapy (35.8%) and combination therapy with at least three drugs (17.0%). Patients on <jats:styled-content style="fixed-case">SU</jats:styled-content> or glinide monotherapy were more likely to alter their treatment frequently (odds ratio [<jats:styled-content style="fixed-case">OR</jats:styled-content>], 1.7; 95% <jats:styled-content style="fixed-case">CI</jats:styled-content>, 1.38–2.08; <jats:italic>P</jats:italic> < 0.001).</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>The status of <jats:styled-content style="fixed-case">OAD</jats:styled-content> use in <jats:styled-content style="fixed-case">C</jats:styled-content>hina is varied with a majority of the patients altering their treatment regimen citing poor effectiveness. These observations from a real‐world setting may serve as guidance for improving diabetes management in <jats:styled-content style="fixed-case">C</jats:styled-content>hina.</jats:p></jats:sec>
Journal
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- Journal of Diabetes
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Journal of Diabetes 7 (2), 166-173, 2014-08-07
Wiley
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Details 詳細情報について
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- CRID
- 1360574095587361664
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- ISSN
- 17530407
- 17530393
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- Data Source
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- Crossref