Male fitness increases when females are eliminated from gene pool: Implications for the Y chromosome
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- William R. Rice
- Department of Biology, Earth and Marine Sciences Building, University of California, 1156 High Street, Santa Cruz, CA 95064
書誌事項
- 公開日
- 1998-05-26
- DOI
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- 10.1073/pnas.95.11.6217
- 公開者
- Proceedings of the National Academy of Sciences
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説明
<jats:p> Because the two sexes share a common gene pool while performing many different biological functions, mutations benefiting one sex may not accumulate due to counter selection in the other sex. In these experiments 99% of a haploid genome of <jats:italic>Drosophila melanogaster</jats:italic> was constrained to segregate like a male-limited Y chromosome for 41 generations, thereby eliminating potential counter selection in females. The synthetic Y chromosomes rapidly accumulated genetic variation that increased male fitness and decreased female fitness. The survival and fertility of females declined when they were mated to males expressing the synthetic Y chromosomes. These results suggests that opposing selection between the sexes may substantially interfere with sex-specific adaptation. They also demonstrate how intersexual evolutionary conflict can lead to perpetual degeneration of the Y via genetic hitchhiking of deleterious mutations. </jats:p>
収録刊行物
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- Proceedings of the National Academy of Sciences
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Proceedings of the National Academy of Sciences 95 (11), 6217-6221, 1998-05-26
Proceedings of the National Academy of Sciences