Hydroxychavicol: a potent xanthine oxidase inhibitor obtained from the leaves of betel, Piper betle

Kazuya Murata, Kikuyo Nakao, Noriko Hirata, Kensuke Namba, Takao Nomi, Yoshihisa Kitamura, Kenzo Moriyama, Takahiro Shintani, Munekazu Iinuma, Hideaki Matsuda

doi:10.1007/s11418-009-0331-y

Hydroxychavicol: a potent xanthine oxidase inhibitor obtained from the leaves of betel, Piper betle

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The screening of Piperaceous plants for xanthine oxidase inhibitory activity revealed that the extract of the leaves of Piper betle possesses potent activity. Activity-guided purification led us to obtain hydroxychavicol as an active principle. Hydroxychavicol is a more potent xanthine oxidase inhibitor than allopurinol, which is clinically used for the treatment of hyperuricemia.

収録刊行物

Journal of Natural Medicines

Journal of Natural Medicines 63 (3), 355-359, 2009-04-22

Springer Science and Business Media LLC

被引用文献 (2)*注記

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CRID

1360574095947940224
DOI

10.1007/s11418-009-0331-y
ISSN

18610293

13403443
PubMed

19387769
Web Site

http://link.springer.com/content/pdf/10.1007/s11418-009-0331-y.pdf

http://link.springer.com/article/10.1007/s11418-009-0331-y/fulltext.html

http://link.springer.com/content/pdf/10.1007/s11418-009-0331-y
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Hydroxychavicol: a potent xanthine oxidase inhibitor obtained from the leaves of betel, Piper betle

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収録刊行物

被引用文献 (2)*注記

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