Reversal of an enzymatic decarboxylation: Thiamin mediated carboxylation of acetaldehyde into pyruvic acid

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<jats:title>Abstract</jats:title><jats:p>Acetaldehyde has been converted into pyruvic acid (42% yield) via the reaction of 2 ‐(1‐hydroxyethyl)thiamin (3) with carbon dioxide at 50 atm. (DMF, 20 C).</jats:p>

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