Controlled rotation of micro-objects using acoustically driven microbubbles

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  • Yuyang Li
    Key Laboratory of Biomimetic Robots and Systems, Ministry of Education, State Key Laboratory of Intelligent Control and Decision of Complex System, Beijing Advanced Innovation Center for Intelligent Robots and Systems, and School of Mechatronical Engineering, Beijing Institute of Technology 1 , Beijing 100081, China
  • Xiaoming Liu
    Key Laboratory of Biomimetic Robots and Systems, Ministry of Education, State Key Laboratory of Intelligent Control and Decision of Complex System, Beijing Advanced Innovation Center for Intelligent Robots and Systems, and School of Mechatronical Engineering, Beijing Institute of Technology 1 , Beijing 100081, China
  • Qiang Huang
    Key Laboratory of Biomimetic Robots and Systems, Ministry of Education, State Key Laboratory of Intelligent Control and Decision of Complex System, Beijing Advanced Innovation Center for Intelligent Robots and Systems, and School of Mechatronical Engineering, Beijing Institute of Technology 1 , Beijing 100081, China
  • Tatsuo Arai
    Key Laboratory of Biomimetic Robots and Systems, Ministry of Education, State Key Laboratory of Intelligent Control and Decision of Complex System, Beijing Advanced Innovation Center for Intelligent Robots and Systems, and School of Mechatronical Engineering, Beijing Institute of Technology 1 , Beijing 100081, China

Description

<jats:p>Micromanipulation has significantly advanced both biomedical and industrial fields. However, there is still an urgent demand for controlled rotational manipulation at the microscale. Here, we report a noncontact rotational micromanipulation method using the acoustically driven microbubble contained in a micropipette. Acoustic vibration of the microbubble close to its resonant frequency was used to generate radiation force and microstreaming in the aqueous medium, allowing for trapping and rotating the micro-object. Simulation and particle visualization of the flow field clearly showed the microstreaming pattern induced by the oscillating microbubble. Experiments with different microbeads demonstrated the highly stable immobilization and rotation that related to the size and density of the microbead. By adjusting the frequency and voltage of the sinusoidal wave applied to the piezoelectric transducer, we demonstrated that the rotation frequency could be controlled over a broad range.</jats:p>

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