Inter-individual differences in human brain structure and morphology link to variation in demographics and behavior
-
- Alberto Llera
- Radboud University Nijmegen, Nijmegen, Netherlands
-
- Thomas Wolfers
- Radboud University Nijmegen, Nijmegen, Netherlands
-
- Peter Mulders
- Radboud University Nijmegen, Nijmegen, Netherlands
-
- Christian F Beckmann
- Radboud University Nijmegen, Nijmegen, Netherlands
説明
<jats:p>We perform a comprehensive integrative analysis of multiple structural MR-based brain features and find for the first-time strong evidence relating inter-individual brain structural variations to a wide range of demographic and behavioral variates across a large cohort of young healthy human volunteers. Our analyses reveal that a robust ‘positive-negative’ spectrum of behavioral and demographic variates, recently associated to covariation in brain function, can already be identified using only structural features, highlighting the importance of careful integration of structural features in any analysis of inter-individual differences in functional connectivity and downstream associations with behavioral/demographic variates.</jats:p>
収録刊行物
-
- eLife
-
eLife 8 2019-07-03
eLife Sciences Publications, Ltd