Sesquiterpenes and Phenolic Compounds from Achillea clypeolata Sesquiterpenes and Phenolic Compounds from Achillea clypeolata

Ingrid Werner, Pavel Mucaji, Armin Presser, Sabine Glasl

doi:10.1515/znb-2007-0219

Sesquiterpenes and Phenolic Compounds from Achillea clypeolata Sesquiterpenes and Phenolic Compounds from Achillea clypeolata

DOI Web Site Web Site XML 被引用文献1件

Ingrid Werner

Department of Pharmacognosy, University of Vienna, PharmaCenter, Althanstraße 14, A-1090 Vienna, Austria
Pavel Mucaji

Department of Pharmacognosy, University of Vienna, PharmaCenter, Althanstraße 14, A-1090 Vienna, Austria
Armin Presser

Institute of Pharmaceutical Sciences, Karl-Franzens-Universit¨at Graz, Universit¨atsplatz 1, A-8010 Graz, Austria
Sabine Glasl

Department of Pharmacognosy, University of Vienna, PharmaCenter, Althanstraße 14, A-1090 Vienna, Austria

抄録

<jats:p>The investigation of a dichloromethane extract of flower heads of Achillea clypeolata collected in Bulgaria led to the isolation of one guaiane (4,10,11-trihydroxy-guaiane, 1), four eudesmanes (4(15)-eudesmene-1β ,11-diol, 2, clypeotriol, 3, 3-epi-clypeotriol, 4, cryptomeridiol, 5), one diterpene (sugeroside, 6) and two phenolic compounds (centaureidin, 7 and scopoletin, 8). Their structures were elucidated by UV/vis, EI- and CI-MS as well as by one- and two-dimensional NMR experiments. 4,10,11-Trihydroxy-guaiane (1) and 3-epi-clypeotriol (4) are reported here for the first time.</jats:p>