Radical Fluoroalkylation of Isocyanides with Fluorinated Sulfones by Visible‐Light Photoredox Catalysis
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- Jian Rong
- Key Laboratory of Organofluorine Chemistry Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences 345 Ling-Ling Road Shanghai 200032 China
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- Ling Deng
- Key Laboratory of Organofluorine Chemistry Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences 345 Ling-Ling Road Shanghai 200032 China
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- Ping Tan
- Key Laboratory of Organofluorine Chemistry Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences 345 Ling-Ling Road Shanghai 200032 China
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- Chuanfa Ni
- Key Laboratory of Organofluorine Chemistry Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences 345 Ling-Ling Road Shanghai 200032 China
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- Yucheng Gu
- Syngenta, Jealott's Hill International Research Centre Bracknell Berkshire RG42 6EY UK
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- Jinbo Hu
- Key Laboratory of Organofluorine Chemistry Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences 345 Ling-Ling Road Shanghai 200032 China
抄録
<jats:title>Abstract</jats:title><jats:p>The radical fluoroalkylation of isocyanides with fluorinated sulfones is enabled by visible‐light photoredox catalysis. A wide range of readily available mono‐, di‐, and trifluoromethyl heteroaryl sulfones can thus be used as efficient radical fluoroalkylation reagents under mild conditions. This method not only describes a new synthetic application of fluorinated sulfones, but also provides a new route to fluoroalkyl radicals.</jats:p>
収録刊行物
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- Angewandte Chemie
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Angewandte Chemie 128 (8), 2793-2797, 2016-01-19
Wiley