Reduced Nucleoprotein Availability Impairs Negative-Sense RNA Virus Replication and Promotes Host Recognition
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- Benjamin E. Nilsson-Payant
- Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA
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- Daniel Blanco-Melo
- Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA
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- Skyler Uhl
- Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA
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- Beatriz Escudero-Pérez
- Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany
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- Silke Olschewski
- Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany
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- Patricia Thibault
- Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA
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- Maryline Panis
- Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA
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- Maria Rosenthal
- Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany
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- César Muñoz-Fontela
- Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany
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- Benhur Lee
- Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA
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- Benjamin R. tenOever
- Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA
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- Stacey Schultz-Cherry
- editor
説明
<jats:p>Negative-sense RNA viruses comprise some of the most important known human pathogens, including influenza A virus, measles virus, and Ebola virus. These viruses possess RNA genomes that are unreadable to the host, as they require specific viral RNA-dependent RNA polymerases in conjunction with other viral proteins, such as nucleoprotein, to be replicated and transcribed.</jats:p>
収録刊行物
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- Journal of Virology
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Journal of Virology 95 (9), e02274-20-, 2021-04-12
American Society for Microbiology
