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- Alex P. Vaz
- Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health, Bethesda, MD 20892, USA.
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- John H. Wittig
- Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health, Bethesda, MD 20892, USA.
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- Sara K. Inati
- Office of the Clinical Director, NINDS, National Institutes of Health, Bethesda, MD 20892, USA.
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- Kareem A. Zaghloul
- Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health, Bethesda, MD 20892, USA.
説明
<jats:title>Human brain activity during memory</jats:title> <jats:p> Animal studies suggest that sequence replay of neuronal activity may underlie memory retrieval and consolidation. However, there is no direct evidence that the replay of spiking activity sequences is important for these processes in the human brain. Vaz <jats:italic>et al.</jats:italic> simultaneously recorded single-unit spikes, local field potential, and intracranial electroencephalography signals in the brain while participants performed a memory task. Sharp wave ripple oscillations in the temporal lobe cortex reflected bursts of neural spiking, and these bursts of spikes organized into sequences during memory formation. These sequences were replayed during successful memory retrieval. The extent of sequence replay during correct recall was related to the extent to which cortical spiking activity was coupled with ripples in the medial temporal lobe. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6482" page="1131" related-article-type="in-this-issue" vol="367" xlink:href="10.1126/science.aba0672">1131</jats:related-article> </jats:p>
収録刊行物
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- Science
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Science 367 (6482), 1131-1134, 2020-03-06
American Association for the Advancement of Science (AAAS)
