Colorectal Cancer Epidemiology: Recent Trends and Impact on Outcomes

  • Firas Baidoun
    Department of Hospital Medicine, Cleveland Clinic Foundation, Cleveland, OH,United States
  • Kholoud Elshiwy
    Faculty of Medicine, Ain Shams University, Cairo,Egypt
  • Yasmine Elkeraie
    High institute of Public Health, Alexandria University, Alexandria,Egypt
  • Zahi Merjaneh
    Department of Hospital Medicine, Cleveland Clinic Foundation, Cleveland, OH,United States
  • George Khoudari
    Department of Hospital Medicine, Cleveland Clinic Foundation, Cleveland, OH,United States
  • Muhammad Talal Sarmini
    Department of Hospital Medicine, Cleveland Clinic Foundation, Cleveland, OH,United States
  • Mohamed Gad
    Department of Internal Medicine, Cleveland Clinic Foundation, Cleveland, OH,United States
  • Muneer Al-Husseini
    Department of Medicine, Ascension St John Hospital, Detroit, Michigan,United States
  • Anas Saad
    Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic Foundation, Cleveland, OH,United States

説明

<jats:sec> <jats:title /> <jats:p>Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer related deaths in the world with an estimated number of 1.8 million new cases and about 881,000 deaths worldwide in 2018. The epidemiology of CRC varies significantly between different regions in the world as well as between different age, gender and racial groups. Multiple factors are involved in this variation, including risk factor exposure, demographic variations in addition to genetic susceptibility and genetic mutations and their effect on the prognosis and treatment response. In this mini-review, we discuss the recent epidemiological trend including the incidence and mortality of colorectal cancer worldwide and the factors affecting these trends.</jats:p> </jats:sec>

収録刊行物

  • Current Drug Targets

    Current Drug Targets 22 (9), 998-1009, 2021-07

    Bentham Science Publishers Ltd.

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