Colonization With Staphylococcus aureus in Atopic Dermatitis Patients: Attempts to Reveal the Unknown
抄録
<jats:p>Atopic dermatitis (AD) patients are massively colonized with<jats:italic>Staphylococcus aureus</jats:italic>(<jats:italic>S. aureus</jats:italic>) in lesional and non-lesional skin. A skin infection may become systemic if left untreated. Of interest, the incidence of multi-drug resistant<jats:italic>S. aureus</jats:italic>(MRSA) in AD patients is higher as compared to a healthy population, which makes treatment even more challenging. Information on the specific genetic background of<jats:italic>S. aureus</jats:italic>accompanying and/or causing AD flares would be of great importance in terms of possible treatment option development. In this review, we summarized the data on the prevalence of<jats:italic>S. aureus</jats:italic>in general in AD skin, and the prevalence of specific clones that might be associated with flares of eczema. We put our special interest in the presence and role of staphylococcal enterotoxins as important virulence factors in the epidemiology of AD-derived<jats:italic>S. aureus</jats:italic>. Also, we summarize the present and potentially useful future anti-staphylococcal treatment.</jats:p>
収録刊行物
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- Frontiers in Microbiology
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Frontiers in Microbiology 11 567090-, 2021-01-11
Frontiers Media SA