DIFFUSE NEONATAL HEMANGIOMATOSIS

DOI PDF 3 Citations
  • Kenton R. Holden
    Department of Pediatrics, Children's Medical and Surgical Center, The Johns Hopkins Hospital, and the Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland
  • Fred Alexander
    Department of Pediatrics, Children's Medical and Surgical Center, The Johns Hopkins Hospital, and the Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland

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Description

<jats:p>Two infants with diffuse neonatal hemangiomatosis are presented. One infant developed thrombocytopenia and bleeding while the other infant with more widely diffuse lesions succumbed to extensive central nervous system involvement.</jats:p> <jats:p>Steroid therapy caused no obvious alteration in either of the patient's course. The vascular lesion in this disease is possibly congenital absence of vessel wall pericytes.</jats:p> <jats:p>Six previous cases of diffuse neonatal hemangiomatosis are briefly reviewed in relation to the sites of the lesions, cause of death and malignant potential.</jats:p>

Journal

  • Pediatrics

    Pediatrics 46 (3), 411-421, 1970-09-01

    American Academy of Pediatrics (AAP)

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