Transfer function analysis of dynamic cerebral autoregulation: A CARNet white paper 2022 update

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  • Ronney B Panerai
    Department of Cardiovascular Sciences, University of Leicester and NIHR Biomedical Research Centre, Leicester, UK
  • Patrice Brassard
    Department of Kinesiology, Faculty of Medicine, and Research Center of the Institut universitaire de cardiologie et de pneumologie de Québec, Université Laval, Québec, QC, Canada
  • Joel S Burma
    Faculty of Kinesiology, University of Calgary, Calgary, AB, Canada
  • Pedro Castro
    Department of Neurology, Centro Hospitalar Universitário de São João, Faculty of Medicine, University of Porto, Porto, Portugal
  • Jurgen AHR Claassen
    Department of Geriatric Medicine and Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, The Netherlands
  • Johannes J van Lieshout
    Department of Internal Medicine, Amsterdam, UMC, The Netherlands and Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham Medical School, Queen’s Medical Centre, UK
  • Jia Liu
    Institute of Advanced Computing and Digital Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen University Town, Shenzhen, China
  • Samuel JE Lucas
    School of Sport, Exercise and Rehabilitation Sciences and Centre for Human Brain Health, University of Birmingham, Birmingham, UK
  • Jatinder S Minhas
    Department of Cardiovascular Sciences, University of Leicester and NIHR Biomedical Research Centre, Leicester, UK
  • Georgios D Mitsis
    Department of Bioengineering, McGill University, Montreal, Québec, QC, Canada
  • Ricardo C Nogueira
    Neurology Department, School of Medicine, Hospital das Clinicas, University of São Paulo, São Paulo, Brazil
  • Shigehiko Ogoh
    Department of Biomedical Engineering, Toyo University, Kawagoe-Shi, Saitama, Japan
  • Stephen J Payne
    Institute of Applied Mechanics, National Taiwan University, Taipei
  • Caroline A Rickards
    Department of Physiology & Anatomy, University of North Texas Health Science Center, Fort Worth, Texas, USA
  • Andrew D Robertson
    Department of Kinesiology and Health Sciences, University of Waterloo, Waterloo, ON, Canada
  • Gabriel D Rodrigues
    Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
  • Jonathan D Smirl
    Faculty of Kinesiology, University of Calgary, Calgary, AB, Canada
  • David M Simpson
    Institute of Sound and Vibration Research, University of Southampton, Southampton, UK

書誌事項

公開日
2022-08-12
資源種別
journal article
権利情報
  • https://creativecommons.org/licenses/by-nc/4.0/
DOI
  • 10.1177/0271678x221119760
公開者
SAGE Publications

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説明

<jats:p>Cerebral autoregulation (CA) refers to the control of cerebral tissue blood flow (CBF) in response to changes in perfusion pressure. Due to the challenges of measuring intracranial pressure, CA is often described as the relationship between mean arterial pressure (MAP) and CBF. Dynamic CA (dCA) can be assessed using multiple techniques, with transfer function analysis (TFA) being the most common. A 2016 white paper by members of an international Cerebrovascular Research Network (CARNet) that is focused on CA strove to improve TFA standardization by way of introducing data acquisition, analysis, and reporting guidelines. Since then, additional evidence has allowed for the improvement and refinement of the original recommendations, as well as for the inclusion of new guidelines to reflect recent advances in the field. This second edition of the white paper contains more robust, evidence-based recommendations, which have been expanded to address current streams of inquiry, including optimizing MAP variability, acquiring CBF estimates from alternative methods, estimating alternative dCA metrics, and incorporating dCA quantification into clinical trials. Implementation of these new and revised recommendations is important to improve the reliability and reproducibility of dCA studies, and to facilitate inter-institutional collaboration and the comparison of results between studies.</jats:p>

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