Impact of age for overall survival in head and neck sarcoma

DOI Web Site 14 References Open Access
  • Hidenori Suzuki
    Department of Head and Neck Surgery, Aichi Cancer Center Hospital, Nagoya, Japan
  • Gaku Takano
    Department of Otolaryngology-Head and Neck Surgery, Nagoya City University Graduate School of Medical Science, Nagoya, Japan
  • Satoshi Tsukushi
    Department of Orthopedic Surgery, Aichi Cancer Center Hospital, Nagoya, Japan
  • Masashi Ando
    Department of Clinical Oncology, Aichi Cancer Center Hospital, Nagoya, Japan
  • Yasushi Yatabe
    Department of Pathology and Molecular Diagnostics, Aichi Cancer Center Hospital, Nagoya, Japan
  • Takeshi Kodaira
    Department of Radiation Oncology, Aichi Cancer Center Hospital, Nagoya, Japan
  • Daisuke Nishikawa
    Department of Head and Neck Surgery, Aichi Cancer Center Hospital, Nagoya, Japan
  • Shintaro Beppu
    Department of Head and Neck Surgery, Aichi Cancer Center Hospital, Nagoya, Japan
  • Yasuhisa Hasegawa
    Department of Head and Neck Surgery, Asahi University, Gifu, Japan.
  • Nobuhiro Hanai
    Department of Head and Neck Surgery, Aichi Cancer Center Hospital, Nagoya, Japan

Abstract

<jats:p>The purpose to the present study is to research the association between age at surgery and survival outcomes of patients with sarcoma in head and neck. Twenty-six patients with head and neck sarcoma who underwent by surgery from 2003 to 2017 were enrolled in the present observation study. Patients who did not undergo chemotherapy were significantly older age at surgery by Mann–Whitney <jats:italic toggle="yes">U</jats:italic> test. Fifty-five was the cutoff age that predicted death by receiver operating curve analysis. Shorter survival rates of overall, disease-specific, local recurrence-free and disease-free were associated with older age by log-rank test. Age (≥55 years/<55 years) was correlated with shorter overall survival by multivariate analysis of Cox’s proportional hazards model adjusting with chemotherapy (absence/presence). In conclusion, older age predicts worse overall survival in head and neck sarcoma.</jats:p>

Journal

  • Medicine

    Medicine 102 (7), e32966-, 2023-02-17

    Ovid Technologies (Wolters Kluwer Health)

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