Diagnostic performance for T1 cancer in colorectal lesions ≥10 mm by optical characterization using magnifying narrow‐band imaging combined with magnifying chromoendoscopy; implications for optimized stratification by Japan Narrow‐band Imaging Expert Team classification
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- Kazuya Hosotani
- Division of Endoscopy Shizuoka Cancer Center Shizuoka Japan
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- Kenichiro Imai
- Division of Endoscopy Shizuoka Cancer Center Shizuoka Japan
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- Kinichi Hotta
- Division of Endoscopy Shizuoka Cancer Center Shizuoka Japan
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- Sayo Ito
- Division of Endoscopy Shizuoka Cancer Center Shizuoka Japan
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- Yoshihiro Kishida
- Division of Endoscopy Shizuoka Cancer Center Shizuoka Japan
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- Yohei Yabuuchi
- Division of Endoscopy Shizuoka Cancer Center Shizuoka Japan
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- Masao Yoshida
- Division of Endoscopy Shizuoka Cancer Center Shizuoka Japan
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- Noboru Kawata
- Division of Endoscopy Shizuoka Cancer Center Shizuoka Japan
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- Naomi Kakushima
- Division of Endoscopy Shizuoka Cancer Center Shizuoka Japan
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- Kohei Takizawa
- Division of Endoscopy Shizuoka Cancer Center Shizuoka Japan
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- Hirotoshi Ishiwatari
- Division of Endoscopy Shizuoka Cancer Center Shizuoka Japan
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- Hiroyuki Matsubayashi
- Division of Endoscopy Shizuoka Cancer Center Shizuoka Japan
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- Hiroyuki Ono
- Division of Endoscopy Shizuoka Cancer Center Shizuoka Japan
抄録
<jats:sec><jats:title>Background</jats:title><jats:p>Magnifying narrow‐band imaging (M‐NBI) and magnifying chromoendoscopy (M‐CE) enable accurate diagnosis of T1 colorectal cancer, but the diagnostic yields from combined M‐NBI and CE have not been fully analyzed. We aimed to evaluate the diagnostic yield of combining Japan NBI Expert Team (JNET) classification using M‐NBI and M‐CE.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>Superficial colorectal lesions ≥10 mm removed at a Japanese tertiary cancer center between February 2016 and December 2018 were included. We analyzed the relationship between JNET classification, M‐CE findings, and histological results based on prospectively collected endoscopic and pathologic data.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>A total of 1573 lesions, including 56 superficial submucosal invasive cancers, 160 deep submucosal invasive cancers, and 81 advanced cancers (≥T2) were analyzed. The probability of deeply invasive cancer (95% confidence interval) was 1.8% (1.1–2.8), 30.1% (25.4–35.1), and 96.6% (91.5–99.1) in JNET Types 2A, 2B, and 3, respectively. The probability of deeply invasive cancer in JNET Type 2B lesions with non‐V, VL, and VH pit pattern was 4.3%, 16.6%, 76.0%, respectively (<jats:italic>P</jats:italic> < 0.001).</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>Our study showed the stratification by M‐NBI using JNET classification and the effect of additional M‐CE for JNET Type 2B lesions.</jats:p></jats:sec>
収録刊行物
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- Digestive Endoscopy
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Digestive Endoscopy 33 (3), 425-432, 2020-08-19
Wiley