Advances in pig models of human diseases

  • Naipeng Hou
    College of Animal Science and Technology China Agricultural University Beijing China
  • Xuguang Du
    Sanya Institute of China Agricultural University Sanya China
  • Sen Wu
    College of Animal Science and Technology China Agricultural University Beijing China

説明

<jats:title>Abstract</jats:title><jats:p>Animal models of human diseases play a critical role in medical research. Pigs are anatomically and physiologically more like humans than are small rodents such as mice, making pigs an attractive option for modeling human diseases. Advances in recent years in genetic engineering have facilitated the rapid rise of pig models for use in studies of human disease. In the present review, we summarize the current status of pig models for human cardiovascular, metabolic, neurodegenerative, and various genetic diseases. We also discuss areas that need to be improved. Animal models of human diseases play a critical role in medical research. Advances in recent years in genetic engineering have facilitated the rapid rise of pig models for use in studies of human disease. In the present review, we summarize the current status of pig models for human cardiovascular, metabolic, neurodegenerative, various genetic diseases and xenotransplantation.</jats:p>

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