Environmental Factors Influencing COVID-19 Incidence and Severity

  • Amanda K. Weaver
    Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley, California, USA;,
  • Jennifer R. Head
    Department of Epidemiology, School of Public Health, University of California, Berkeley, Berkeley, California, USA;
  • Carlos F. Gould
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA;
  • Elizabeth J. Carlton
    Department of Environmental and Occupational Health, Colorado School of Public Health, University of Colorado, Anschutz, Aurora, Colorado, USA;
  • Justin V. Remais
    Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley, California, USA;,

説明

<jats:p> Emerging evidence supports a link between environmental factors—including air pollution and chemical exposures, climate, and the built environment—and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission and coronavirus disease 2019 (COVID-19) susceptibility and severity. Climate, air pollution, and the built environment have long been recognized to influence viral respiratory infections, and studies have established similar associations with COVID-19 outcomes. More limited evidence links chemical exposures to COVID-19. Environmental factors were found to influence COVID-19 through four major interlinking mechanisms: increased risk of preexisting conditions associated with disease severity; immune system impairment; viral survival and transport; and behaviors that increase viral exposure. Both data and methodologic issues complicate the investigation of these relationships, including reliance on coarse COVID-19 surveillance data; gaps in mechanistic studies; and the predominance of ecological designs. We evaluate the strength of evidence for environment–COVID-19 relationships and discuss environmental actions that might simultaneously address the COVID-19 pandemic, environmental determinants of health, and health disparities. </jats:p>

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