Bromelain and Nisin: The Natural Antimicrobials with High Potential in Biomedicine
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- Urška Jančič
- Institute of Engineering Materials and Design, Faculty of Mechanical Engineering, University of Maribor, Smetanova ulica 17, 2000 Maribor, Slovenia
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- Selestina Gorgieva
- Institute of Engineering Materials and Design, Faculty of Mechanical Engineering, University of Maribor, Smetanova ulica 17, 2000 Maribor, Slovenia
書誌事項
- 公開日
- 2021-12-29
- 権利情報
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- https://creativecommons.org/licenses/by/4.0/
- DOI
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- 10.3390/pharmaceutics14010076
- 公開者
- MDPI AG
説明
<jats:p>Infectious diseases along with various cancer types are among the most significant public health problems and the leading cause of death worldwide. The situation has become even more complex with the rapid development of multidrug-resistant microorganisms. New drugs are urgently needed to curb the increasing spread of diseases in humans and livestock. Promising candidates are natural antimicrobial peptides produced by bacteria, and therapeutic enzymes, extracted from medicinal plants. This review highlights the structure and properties of plant origin bromelain and antimicrobial peptide nisin, along with their mechanism of action, the immobilization strategies, and recent applications in the field of biomedicine. Future perspectives towards the commercialization of new biomedical products, including these important bioactive compounds, have been highlighted.</jats:p>
収録刊行物
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- Pharmaceutics
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Pharmaceutics 14 (1), 76-, 2021-12-29
MDPI AG