Concise Synthesis of Procyanidin B2 3,3′′-Digallate Using Yb(OTf)3-Mediated Self-Condensation
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- Yuuri Tanaka
- Graduate School of Science and Technology, Department of Agriculture, Shinshu University
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- Shu-hei Kobayashi
- Graduate School of Science and Technology, Department of Agriculture, Shinshu University
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- Atsushi Kawamura
- Department of Biomolecular Innovation, Institute for Biomedical Sciences, Interdisciplinary Cluster for Cutting Edge Research, Shinshu University
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- Hidefumi Makabe
- Graduate School of Science and Technology, Department of Agriculture, Shinshu University
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- Yasunao Hattori
- Center for Instrumental Analysis, Kyoto Pharmaceutical University
抄録
<jats:title>Abstract</jats:title><jats:p>Lewis acid mediated self-condensation of epicatechin gallate derivative was examined. We found that Yb(OTf)3 afforded good yield of the dimeric epicatechin gallate derivative. The condensed product was applied to the synthesis of procyanidin B2 3,3′′-digallate.</jats:p>
収録刊行物
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- Synlett
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Synlett 33 (11), 1071-1074, 2022-05-09
Georg Thieme Verlag KG