Serum tocilizumab trough concentration can be used to monitor systemic IL-6 receptor blockade in patients with rheumatoid arthritis: a prospective observational cohort study

EL Kneepkens

Department of Rheumatology, Amsterdam Rheumatology and immunology Centre, location Reade, Amsterdam, The Netherlands
IAM van den Oever

Department of Rheumatology, Amsterdam Rheumatology and immunology Centre, location Reade, Amsterdam, The Netherlands
CH Plasencia

Department of Rheumatology, La Paz hospital Madrid, Spain
D Pascual-Salcedo

Immunology Unit, La Paz Hospital Madrid, Spain
A de Vries

Sanquin Diagnostic Services Amsterdam, The Netherlands
M Hart

Department of Immunopathology, Sanquin Research and Landsteiner Laboratory, Academic Medical Centre Amsterdam, The Netherlands
MT Nurmohamed

Department of Rheumatology, Amsterdam Rheumatology and immunology Centre, location Reade, Amsterdam, The Netherlands
A Balsa

Department of Rheumatology, La Paz hospital Madrid, Spain
T Rispens

Department of Immunopathology, Sanquin Research and Landsteiner Laboratory, Academic Medical Centre Amsterdam, The Netherlands
G Wolbink

Department of Rheumatology, Amsterdam Rheumatology and immunology Centre, location Reade, Amsterdam, The Netherlands