Four weeks of vitamin D supplementation improves nitric oxide-mediated microvascular function in college-aged African Americans
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- S. Tony Wolf
- Department of Kinesiology, The Pennsylvania State University, University Park, Pennsylvania
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- Nina G. Jablonski
- Department of Anthropology, The Pennsylvania State University, University Park, Pennsylvania
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- Sara B. Ferguson
- Department of Dermatology, The Penn State Hershey Medical Group, State College, Pennsylvania
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- Lacy M. Alexander
- Department of Kinesiology, The Pennsylvania State University, University Park, Pennsylvania
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- W. Larry Kenney
- Department of Kinesiology, The Pennsylvania State University, University Park, Pennsylvania
書誌事項
- 公開日
- 2020-10-01
- DOI
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- 10.1152/ajpheart.00631.2020
- 公開者
- American Physiological Society
この論文をさがす
説明
<jats:p> Endothelial dysfunction, an antecedent to overt cardiovascular disease (CVD), is observed earlier and more frequently in otherwise healthy African Americans (AAs) when compared with other ethnic groups. Vitamin D may modulate endothelial function, and darkened skin pigmentation increases risk of vitamin D deficiency. We show that 4 wk of 2,000 IU/day vitamin D supplementation improves microvascular responses to local heating in AAs. Ensuring adequate vitamin D status may mitigate development of cardiovascular dysfunction in this at-risk population. </jats:p>
収録刊行物
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- American Journal of Physiology-Heart and Circulatory Physiology
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American Journal of Physiology-Heart and Circulatory Physiology 319 (4), H906-H914, 2020-10-01
American Physiological Society
