The PATRIC Bioinformatics Resource Center: expanding data and analysis capabilities

  • James J Davis
    University of Chicago Consortium for Advanced Science and Engineering, University of Chicago, Chicago, IL 60637, USA
  • Alice R Wattam
    Division of Data Science and Learning, Argonne National Laboratory, Argonne, IL 60439, USA
  • Ramy K Aziz
    Department of Microbiology and Immunology, Faculty of Pharmacy, Cairo University, 11562 Cairo, Egypt
  • Thomas Brettin
    University of Chicago Consortium for Advanced Science and Engineering, University of Chicago, Chicago, IL 60637, USA
  • Ralph Butler
    Division of Data Science and Learning, Argonne National Laboratory, Argonne, IL 60439, USA
  • Rory M Butler
    Division of Data Science and Learning, Argonne National Laboratory, Argonne, IL 60439, USA
  • Philippe Chlenski
    Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA
  • Neal Conrad
    University of Chicago Consortium for Advanced Science and Engineering, University of Chicago, Chicago, IL 60637, USA
  • Allan Dickerman
    Biocomplexity Institute and Initiative, University of Virginia, Charlottesville, VA 22904, USA
  • Emily M Dietrich
    University of Chicago Consortium for Advanced Science and Engineering, University of Chicago, Chicago, IL 60637, USA
  • Joseph L Gabbard
    Virginia Tech, Blacksburg, VA 24061, USA
  • Svetlana Gerdes
    Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA
  • Andrew Guard
    University of Chicago Consortium for Advanced Science and Engineering, University of Chicago, Chicago, IL 60637, USA
  • Ronald W Kenyon
    Biocomplexity Institute and Initiative, University of Virginia, Charlottesville, VA 22904, USA
  • Dustin Machi
    Biocomplexity Institute and Initiative, University of Virginia, Charlottesville, VA 22904, USA
  • Chunhong Mao
    Biocomplexity Institute and Initiative, University of Virginia, Charlottesville, VA 22904, USA
  • Dan Murphy-Olson
    University of Chicago Consortium for Advanced Science and Engineering, University of Chicago, Chicago, IL 60637, USA
  • Marcus Nguyen
    University of Chicago Consortium for Advanced Science and Engineering, University of Chicago, Chicago, IL 60637, USA
  • Eric K Nordberg
    Transportation Institute, Virginia Tech University, Blacksburg, VA 24061, USA
  • Gary J Olsen
    Department of Microbiology, University of Illinois, Urbana, IL 61801, USA
  • Robert D Olson
    University of Chicago Consortium for Advanced Science and Engineering, University of Chicago, Chicago, IL 60637, USA
  • Jamie C Overbeek
    University of Chicago Consortium for Advanced Science and Engineering, University of Chicago, Chicago, IL 60637, USA
  • Ross Overbeek
    University of Chicago Consortium for Advanced Science and Engineering, University of Chicago, Chicago, IL 60637, USA
  • Bruce Parrello
    University of Chicago Consortium for Advanced Science and Engineering, University of Chicago, Chicago, IL 60637, USA
  • Gordon D Pusch
    Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA
  • Maulik Shukla
    University of Chicago Consortium for Advanced Science and Engineering, University of Chicago, Chicago, IL 60637, USA
  • Chris Thomas
    University of Chicago Consortium for Advanced Science and Engineering, University of Chicago, Chicago, IL 60637, USA
  • Margo VanOeffelen
    Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA
  • Veronika Vonstein
    Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA
  • Andrew S Warren
    Biocomplexity Institute and Initiative, University of Virginia, Charlottesville, VA 22904, USA
  • Fangfang Xia
    University of Chicago Consortium for Advanced Science and Engineering, University of Chicago, Chicago, IL 60637, USA
  • Dawen Xie
    Biocomplexity Institute and Initiative, University of Virginia, Charlottesville, VA 22904, USA
  • Hyunseung Yoo
    University of Chicago Consortium for Advanced Science and Engineering, University of Chicago, Chicago, IL 60637, USA
  • Rick Stevens
    Computing Environment and Life Sciences, Argonne National Laboratory, Argonne, IL 60439, USA

書誌事項

公開日
2019-10-31
DOI
  • 10.1093/nar/gkz943
公開者
Oxford University Press (OUP)

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説明

<jats:title>Abstract</jats:title> <jats:p>The PathoSystems Resource Integration Center (PATRIC) is the bacterial Bioinformatics Resource Center funded by the National Institute of Allergy and Infectious Diseases (https://www.patricbrc.org). PATRIC supports bioinformatic analyses of all bacteria with a special emphasis on pathogens, offering a rich comparative analysis environment that provides users with access to over 250 000 uniformly annotated and publicly available genomes with curated metadata. PATRIC offers web-based visualization and comparative analysis tools, a private workspace in which users can analyze their own data in the context of the public collections, services that streamline complex bioinformatic workflows and command-line tools for bulk data analysis. Over the past several years, as genomic and other omics-related experiments have become more cost-effective and widespread, we have observed considerable growth in the usage of and demand for easy-to-use, publicly available bioinformatic tools and services. Here we report the recent updates to the PATRIC resource, including new web-based comparative analysis tools, eight new services and the release of a command-line interface to access, query and analyze data.</jats:p>

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