Linking a Gene Cluster to Atranorin, a Major Cortical Substance of Lichens, through Genetic Dereplication and Heterologous Expression

  • Wonyong Kim
    Korean Lichen Research Institute, Sunchon National University, Suncheon, South Korea<?A3B2 show [zaq no="AQGRid1"]?>
  • Rundong Liu
    Korean Lichen Research Institute, Sunchon National University, Suncheon, South Korea<?A3B2 show [zaq no="AQGRid1"]?>
  • Sunmin Woo
    Research Institute of Pharmaceutical Sciences, College of Pharmacy, Sookmyung Women's University, Seoul, South Korea
  • Kyo Bin Kang
    Research Institute of Pharmaceutical Sciences, College of Pharmacy, Sookmyung Women's University, Seoul, South Korea
  • Hyun Park
    Division of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, South Korea
  • Young Hyun Yu
    College of Pharmacy, Sunchon National University, Suncheon, South Korea
  • Hyung-Ho Ha
    College of Pharmacy, Sunchon National University, Suncheon, South Korea
  • Seung-Yoon Oh
    Department of Biology and Chemistry, Changwon National University, Changwon, South Korea
  • Ji Ho Yang
    Korean Lichen Research Institute, Sunchon National University, Suncheon, South Korea<?A3B2 show [zaq no="AQGRid1"]?>
  • Hangun Kim
    College of Pharmacy, Sunchon National University, Suncheon, South Korea
  • Sung-Hwan Yun
    Department of Medical Sciences, Soonchunhyang University, Asan, South Korea
  • Jae-Seoun Hur
    Korean Lichen Research Institute, Sunchon National University, Suncheon, South Korea<?A3B2 show [zaq no="AQGRid1"]?>

説明

<jats:p>Lichens play significant roles in ecosystem function and comprise about 20% of all known fungi. Polyketide-derived natural products accumulate in the cortical and medullary layers of lichen thalli, some of which play key roles in protection from biotic and abiotic stresses (e.g., herbivore attacks and UV irradiation).</jats:p>

収録刊行物

  • mBio

    mBio 12 (3), 2021-06-29

    American Society for Microbiology

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