Improving outcome of malignant brain tumours in very young children: a population‐based study in Finland during 1975‐93

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Abstract

<jats:p><jats:bold>Abstract</jats:bold> Sixty‐four children with malignant brain tumours diagnosed at less than 3 years of age were reported to the Finnish Cancer Registry from 1975 to 1993. The survival rate has improved significantly: the 5‐year survival rate was 26% for all children, 13% for children diagnosed during 1975‐85 (<jats:italic>n</jats:italic>= 30) and 40% for those diagnosed during 1986‐93 (<jats:italic>n</jats:italic>= 4). Of the surviving children in 1986‐93, 43% were categorized in Bloom's group I or II and could lead active lives without major disabilities. The remaining children had severe neurologic late complications, such as hemiplegia, intractable seizures, and mental retardation.</jats:p>

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