- 【Updated on May 12, 2025】 Integration of CiNii Dissertations and CiNii Books into CiNii Research
- Trial version of CiNii Research Knowledge Graph Search feature is available on CiNii Labs
- 【Updated on June 30, 2025】Suspension and deletion of data provided by Nikkei BP
- Regarding the recording of “Research Data” and “Evidence Data”
Results of the interim analysis of a prospective, multicenter, observational study of small subepithelial lesions in the stomach
-
- Masaya Iwamuro
- Department of Gastroenterology and Hepatology Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama Japan
-
- Toshiharu Mitsuhashi
- Center for Innovative Clinical Medicine Okayama University Hospital Okayama Japan
-
- Tomoki Inaba
- Department of Gastroenterology Kagawa Prefectural Central Hospital Kagawa Japan
-
- Kazuhiro Matsueda
- Department of Gastroenterology and Hepatology Kurashiki Central Hospital Okayama Japan
-
- Teruya Nagahara
- Department of Gastroenterology Mitoyo General Hospital Kagawa Japan
-
- Yoji Takeuchi
- Department of Gastrointestinal Oncology Osaka International Cancer Institute Osaka Japan
-
- Hisashi Doyama
- Department of Gastroenterology Ishikawa Prefectural Central Hospital Ishikawa Japan
-
- Masakatsu Mizuno
- Department of Internal Medicine Japanese Red Cross Mihara Hospital Hiroshima Japan
-
- Tomoyuki Yada
- Department of Gastroenterology and Hepatology Kohnodai Hospital, National Center for Global Health and Medicine Chiba Japan
-
- Yoshinari Kawai
- Department of Gastroenterology Onomichi Municipal Hospital Hiroshima Japan
-
- Jun Nakamura
- Department of Endoscopy Fukushima Medical University Hospital Fukushima Japan
-
- Minoru Matsubara
- Department of Internal Medicine Sumitomo Besshi Hospital Ehime Japan
-
- Hiroko Nebiki
- Department of Gastroenterology Osaka City General Hospital Osaka Japan
-
- Keiko Niimi
- Department of Gastroenterology The University of Tokyo Hospital Tokyo Japan
-
- Tatsuya Toyokawa
- Department of Gastroenterology National Hospital Organization Fukuyama Medical Center Hiroshima Japan
-
- Ryuta Takenaka
- Department of Internal Medicine Tsuyama Chuo Hospital Okayama Japan
-
- Sho Takeda
- Department of Internal Medicine Teraoka Memorial Hospital Hiroshima Japan
-
- Shouichi Tanaka
- Department of Gastroenterology National Hospital Organization Iwakuni Clinical Center Yamaguchi Japan
-
- Mamoru Nishimura
- Department of Internal Medicine Okayama City Hospital Okayama Japan
-
- Takao Tsuzuki
- Department of Internal Medicine Japanese Red Cross Society Himeji Hospital Hyogo Japan
-
- Kazuya Akahoshi
- Department of Gastroenterology Iizuka Hospital Fukuoka Japan
-
- Takahisa Furuta
- Center for Clinical Research Hamamatsu University School of Medicine Shizuoka Japan
-
- Ken Haruma
- Department of General Internal Medicine 2 Kawasaki Medical School General Medical Center Okayama Japan
-
- Hiroyuki Okada
- Department of Internal Medicine Japanese Red Cross Society Himeji Hospital Hyogo Japan
Search this article
Description
<jats:sec><jats:title>Objectives</jats:title><jats:p>Long‐term outcomes of gastric subepithelial lesions have not been elucidated. To reveal the natural history, we initiated a prospective, 10‐year follow‐up of patients with small (≤20 mm) gastric subepithelial lesions in September 2014. Here, we report the results of an interim analysis of a prospective observational study.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>In total, 567 patients with 610 lesions were prospectively registered between September 2014 and August 2016. The location, size, morphology, and number of subepithelial lesions were recorded on a web‐based case report form. This study has been conducted as an Academic Committee Working Group of the Japan Gastroenterological Endoscopy Society.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>The endoscopic follow‐up period was 4.60 ± 1.73 years (mean ± standard deviation), and survival data were investigated for 5.28 ± 1.68 years. This interim analysis revealed that the estimated cumulative incidence of a size increase ≥5 mm, after accounting for patients' death and resection of the tumor as competing risk events, was 4.5% at 5 years. In addition, the estimated cumulative incidence of lesion size increase ≥5 mm or resection of lesions was 7.9% at 5 years, and that of size increase ≥10 mm or resection of lesions was 4.5% at 5 years.</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>These results indicate that approximately one in 13 patients with small (≤20 mm) gastric subepithelial lesions may require resection or further investigation for increased tumor size (≥5 mm) within 5 years.</jats:p></jats:sec>
Journal
-
- Digestive Endoscopy
-
Digestive Endoscopy 36 (3), 323-331, 2023-06-15
Wiley