Cell Polarity and Patterning by PIN Trafficking through Early Endosomal Compartments in Arabidopsis thaliana
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- Christian Luschnig
- editor
説明
PIN-FORMED (PIN) proteins localize asymmetrically at the plasma membrane and mediate intercellular polar transport of the plant hormone auxin that is crucial for a multitude of developmental processes in plants. PIN localization is under extensive control by environmental or developmental cues, but mechanisms regulating PIN localization are not fully understood. Here we show that early endosomal components ARF GEF BEN1 and newly identified Sec1/Munc18 family protein BEN2 are involved in distinct steps of early endosomal trafficking. BEN1 and BEN2 are collectively required for polar PIN localization, for their dynamic repolarization, and consequently for auxin activity gradient formation and auxin-related developmental processes including embryonic patterning, organogenesis, and vasculature venation patterning. These results show that early endosomal trafficking is crucial for cell polarity and auxin-dependent regulation of plant architecture.
収録刊行物
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- PLoS Genetics
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PLoS Genetics 9 (5), e1003540-, 2013-05-30
Public Library of Science (PLoS)
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キーワード
- Cytoplasmic Dyneins
- EFFLUX CARRIER
- PROTEINS
- ENDOCYTOSIS
- DEPENDENT AUXIN GRADIENTS
- Arabidopsis
- TRANSPORT PATHWAYS
- Endosomes
- QH426-470
- Plant Roots
- Munc18 Proteins
- Gene Expression Regulation, Plant
- Genetics
- Transport Vesicles
- GOLGI NETWORK/EARLY ENDOSOME
- Indoleacetic Acids
- Arabidopsis Proteins
- PLANT DEVELOPMENT
- Cell Membrane
- ROOT-MERISTEM
- Biology and Life Sciences
- Cell Polarity
- Biological Transport
- Alcohol Oxidoreductases
- Protein Transport
- SNARE
- 570 Life sciences; biology
- MEMBRANE
- Research Article
詳細情報 詳細情報について
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- CRID
- 1360846644312846592
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- ISSN
- 15537404
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- HANDLE
- 1854/LU-4110283
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- PubMed
- 23737757
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- 資料種別
- journal article
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- データソース種別
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- Crossref
- KAKEN
- OpenAIRE
