The genus Codonopsis (Campanulaceae): a review of phytochemistry, bioactivity and quality control
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説明
<jats:title>Abstract</jats:title> <jats:p> <jats:italic>Codonopsis</jats:italic>, in the family Campanulaceae, is a genus containing 42 species of dicotyledonous herbaceous perennial plants, predominantly found in Central, East and South Asia. Several <jats:italic>Codonopsis</jats:italic> species are widely used in traditional medicine and are considered to have multiple medicinal properties. Among the <jats:italic>Codonopsis</jats:italic> species, <jats:italic>Codonopsis pilosula</jats:italic> (Franch.) Nannf. and <jats:italic>C. lanceolata</jats:italic> (Sieb. et Zucc.) Benth. & Hook. f. ex Trautv. are more popular than others according to the findings, especially phytochemical and bioactive studies. Phytochemical research shows that <jats:italic>Codonopsis</jats:italic> species contain mainly polyacetylenes, phenylpropanoids, alkaloids, triterpenoids and polysaccharides, which contribute to multiple bioactivities. However, the mechanisms of their bioactivities need to be further elucidated. The less popular <jats:italic>Codonopsis</jats:italic> species remain to be studied and exploited. In addition, although a series of methods for the quality evaluation of <jats:italic>Codonopsis</jats:italic> species have been developed, a feasible and reliable approach to the efficacious and safe use of various <jats:italic>Codonopsis</jats:italic> species is still needed, with considering botanical origin, chemical constituents and bioactive effects. This review aims to provide up-to-date and comprehensive information on the phytochemistry, bioactivity and quality control of medicinal plants in the genus <jats:italic>Codonopsis</jats:italic> and to highlight current gaps in knowledge, which is useful for the wider development of the <jats:italic>Codonopsis</jats:italic> genus.</jats:p>
収録刊行物
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- Journal of Natural Medicines
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Journal of Natural Medicines 69 (1), 1-21, 2014-08-07
Springer Science and Business Media LLC
