A facile preparation of functional cycloalkynes <i>via</i> an azide-to-cycloalkyne switching approach

  • Suguru Yoshida
    Laboratory of Chemical Bioscience, Institute of Biomaterials and Bioengineering
  • Tomoko Kuribara
    Laboratory of Chemical Bioscience, Institute of Biomaterials and Bioengineering
  • Harumi Ito
    Laboratory of Chemical Bioscience, Institute of Biomaterials and Bioengineering
  • Tomohiro Meguro
    Laboratory of Chemical Bioscience, Institute of Biomaterials and Bioengineering
  • Yoshitake Nishiyama
    Laboratory of Chemical Bioscience, Institute of Biomaterials and Bioengineering
  • Fumika Karaki
    Laboratory of Chemical Bioscience, Institute of Biomaterials and Bioengineering
  • Yasutomo Hatakeyama
    Laboratory of Chemical Bioscience, Institute of Biomaterials and Bioengineering
  • Yuka Koike
    Common Facilities Unit
  • Isao Kii
    Laboratory for Pathophysiological and Health Science
  • Takamitsu Hosoya
    Laboratory of Chemical Bioscience, Institute of Biomaterials and Bioengineering

書誌事項

公開日
2019
資源種別
journal article
権利情報
  • http://creativecommons.org/licenses/by/3.0/
DOI
  • 10.1039/c9cc01113g
公開者
Royal Society of Chemistry (RSC)

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説明

<p>Terminal alkyne-selective click conjugation of diynes bearing strained and terminal alkyne moieties with functional azides has been achieved by transient protection of strained alkynes <italic>via</italic> complexation with copper to easily afford various functional cycloalkynes.</p>

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