Molecular and cellular neurocardiology: development, and cellular and molecular adaptations to heart disease

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  • Beth A. Habecker
    Department of Physiology and Pharmacology, Department of Medicine Division of Cardiovascular Medicine and Knight Cardiovascular Institute Oregon Health and Science University Portland OR 97239 USA
  • Mark E. Anderson
    Johns Hopkins Department of Medicine Johns Hopkins School of Medicine Baltimore MD 21287 USA
  • Susan J. Birren
    Department of Biology, Volen Center for Complex Systems Brandeis University Waltham MA 02453 USA
  • Keiichi Fukuda
    Department of Cardiology Keio University School of Medicine 35‐Shinanomachi Shinjuku‐ku Tokyo 160–8582 Japan
  • Neil Herring
    Burdon Sanderson Cardiac Science Centre, Department of Physiology, Anatomy and Genetics University of Oxford Parks Road Oxford OX1 3PT UK
  • Donald B. Hoover
    Department of Biomedical Sciences, Center of Excellence in Inflammation, Infectious Disease and Immunity, James H. Quillen College of Medicine East Tennessee State University Johnson City TN 37614 USA
  • Hideaki Kanazawa
    Department of Cardiology Keio University School of Medicine 35‐Shinanomachi Shinjuku‐ku Tokyo 160–8582 Japan
  • David J. Paterson
    Burdon Sanderson Cardiac Science Centre, Department of Physiology, Anatomy and Genetics University of Oxford Parks Road Oxford OX1 3PT UK
  • Crystal M. Ripplinger
    Department of Pharmacology University of California Davis CA 95616 USA

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<jats:sec><jats:title>Abstract</jats:title><jats:p>The nervous system and cardiovascular system develop in concert and are functionally interconnected in both health and disease. This white paper focuses on the cellular and molecular mechanisms that underlie neural–cardiac interactions during development, during normal physiological function in the mature system, and during pathological remodelling in cardiovascular disease. The content on each subject was contributed by experts, and we hope that this will provide a useful resource for newcomers to neurocardiology as well as aficionados.</jats:p></jats:sec>

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