Blockade of Interleukin-6 Signaling Suppresses Not Only Th17 but Also Interphotoreceptor Retinoid Binding Protein–Specific Th1 by Promoting Regulatory T Cells in Experimental Autoimmune Uveoretinitis

  • Hiroshi Haruta
    From the Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan; the 2Laboratory for Immune Signal, National Institute of Biomedical Innovation, Osaka, Japan;
  • Nobuyuki Ohguro
    From the Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan;
  • Minoru Fujimoto
    the Laboratory for Immune Signal, National Institute of Biomedical Innovation, Osaka, Japan;
  • Satoshi Hohki
    From the Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan; the 2Laboratory for Immune Signal, National Institute of Biomedical Innovation, Osaka, Japan;
  • Fumitaka Terabe
    the Laboratory for Immune Signal, National Institute of Biomedical Innovation, Osaka, Japan;
  • Satoshi Serada
    the Laboratory for Immune Signal, National Institute of Biomedical Innovation, Osaka, Japan;
  • Shintaro Nomura
    the Department of Animal Bioscience, Nagahama Institute of Bio-Science and Technology, Shiga, Japan; and
  • Kohji Nishida
    From the Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan;
  • Tadamitsu Kishimoto
    the Laboratory of Immune Regulation, Graduate School of Frontier Biosciences, Osaka University, Osaka, Japan.
  • Tetsuji Naka
    the Laboratory for Immune Signal, National Institute of Biomedical Innovation, Osaka, Japan;

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