Diagnostic performance of peripheral leukocyte telomere G‐tail length for detecting breast cancer
-
- Yumiko Koi
- Surgical Oncology Division of Radiation Biology and Medicine Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan
-
- Yasuhiro Tsutani
- Department of Surgical Oncology Research Center for Radiation Casualty Medicine Research Institute for Radiation Biology and Medicine Hiroshima University Hiroshima Japan
-
- Yukie Nishiyama
- Department of Cellular and Molecular Biology Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan
-
- Miyuki Kanda
- Collaborative Laboratory of Liquid Biopsy Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan
-
- Yoshitomo Shiroma
- Department of Cellular and Molecular Biology Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan
-
- Yuki Yamamoto
- Department of Cellular and Molecular Biology Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan
-
- Shinsuke Sasada
- Department of Surgical Oncology Research Center for Radiation Casualty Medicine Research Institute for Radiation Biology and Medicine Hiroshima University Hiroshima Japan
-
- Tomoyuki Akita
- Department of Epidemiology Infectious Disease Control and Prevention Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan
-
- Norio Masumoto
- Department of Surgical Oncology Research Center for Radiation Casualty Medicine Research Institute for Radiation Biology and Medicine Hiroshima University Hiroshima Japan
-
- Takayuki Kadoya
- Department of Surgical Oncology Research Center for Radiation Casualty Medicine Research Institute for Radiation Biology and Medicine Hiroshima University Hiroshima Japan
-
- Ryou‐u Takahashi
- Department of Cellular and Molecular Biology Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan
-
- Junko Tanaka
- Department of Epidemiology Infectious Disease Control and Prevention Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan
-
- Morihito Okada
- Department of Surgical Oncology Research Center for Radiation Casualty Medicine Research Institute for Radiation Biology and Medicine Hiroshima University Hiroshima Japan
-
- Hidetoshi Tahara
- Department of Cellular and Molecular Biology Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan
この論文をさがす
説明
<jats:title>Abstract</jats:title><jats:p>The telomere G‐tail (G‐tail) plays an essential role in maintaining chromosome stability. In this study, we assessed the leukocyte G‐tail length of breast cancer (BC) patients and cancer‐free individuals and evaluated the association between the G‐tail length and the presence of BC. A significant shortening of the median G‐tail length was observed in BC patients compared with cancer‐free individuals and was found in the early phase of BC. Our study indicated that the leukocyte G‐tail length might be a potential biomarker for BC detection.</jats:p>
収録刊行物
-
- Cancer Science
-
Cancer Science 111 (5), 1856-1861, 2020-04-06
Wiley
- Tweet
キーワード
詳細情報 詳細情報について
-
- CRID
- 1360849945421197312
-
- ISSN
- 13497006
- 13479032
-
- 資料種別
- journal article
-
- データソース種別
-
- Crossref
- KAKEN
- OpenAIRE
