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- Daria Mordovkina
- Institute of Protein Research, Russian Academy of Sciences, Pushchino 142290, Russia
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- Dmitry N. Lyabin
- Institute of Protein Research, Russian Academy of Sciences, Pushchino 142290, Russia
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- Egor A. Smolin
- Institute of Protein Research, Russian Academy of Sciences, Pushchino 142290, Russia
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- Ekaterina M. Sogorina
- Institute of Protein Research, Russian Academy of Sciences, Pushchino 142290, Russia
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- Lev P. Ovchinnikov
- Institute of Protein Research, Russian Academy of Sciences, Pushchino 142290, Russia
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- Irina Eliseeva
- Institute of Protein Research, Russian Academy of Sciences, Pushchino 142290, Russia
説明
<jats:p>Y-box binding proteins (YB proteins) are DNA/RNA-binding proteins belonging to a large family of proteins with the cold shock domain. Functionally, these proteins are known to be the most diverse, although the literature hardly offers any molecular mechanisms governing their activities in the cell, tissue, or the whole organism. This review describes the involvement of YB proteins in RNA-dependent processes, such as mRNA packaging into mRNPs, mRNA translation, and mRNA stabilization. In addition, recent data on the structural peculiarities of YB proteins underlying their interactions with nucleic acids are discussed.</jats:p>
収録刊行物
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- Biomolecules
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Biomolecules 10 (4), 591-, 2020-04-11
MDPI AG