Correlation of Melting Temperature and Cesium Chloride Buoyant Density of Bacterial Deoxyribonucleic Acid

  • M. Mandel
    Section of Molecular Biology, The University of Texas M. D. Anderson Hospital and Tumor Institute at Houston, Houston, Texas 77025
  • Levi Igambi
    Section of Molecular Biology, The University of Texas M. D. Anderson Hospital and Tumor Institute at Houston, Houston, Texas 77025
  • Janet Bergendahl
    Section of Molecular Biology, The University of Texas M. D. Anderson Hospital and Tumor Institute at Houston, Houston, Texas 77025
  • M. L. Dodson
    Section of Molecular Biology, The University of Texas M. D. Anderson Hospital and Tumor Institute at Houston, Houston, Texas 77025
  • E. Scheltgen
    Section of Molecular Biology, The University of Texas M. D. Anderson Hospital and Tumor Institute at Houston, Houston, Texas 77025

書誌事項

公開日
1970-02
権利情報
  • https://journals.asm.org/non-commercial-tdm-license
DOI
  • 10.1128/jb.101.2.333-338.1970
公開者
American Society for Microbiology

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説明

<jats:p> Samples of bacterial deoxyribonucleic acid from bacteria having guanine plus cytosine (GC) contents in the range of 27 to 72 moles per cent GC were analyzed by optical melting (T <jats:sub>m</jats:sub> ) and equilibrium buoyant density methods. The relation between these properties is shown to be linear. The relative value of 1.99 moles per cent GC per degree C change in T <jats:sub>m</jats:sub> is calculated, and a reference method for the calculation of GC contents relative to a standard is derived. </jats:p>

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