Positive Affectivity Is Dampened in Youths With Histories of Major Depression and Their Never-Depressed Adolescent Siblings

  • Maria Kovacs
    Department of Psychiatry, University of Pittsburgh School of Medicine
  • Lauren M. Bylsma
    Department of Psychiatry, University of Pittsburgh School of Medicine
  • Ilya Yaroslavsky
    Department of Psychology, Cleveland State University
  • Jonathan Rottenberg
    Department of Psychology, University of South Florida
  • Charles J. George
    WPIC, University of Pittsburgh Medical Center
  • Enikö Kiss
    Department of Child and Adolescent Psychiatry, University of Szeged, Hungary
  • Kitti Halas
    Department of Child and Adolescent Psychiatry, University of Szeged, Hungary
  • István Benák
    Department of Child and Adolescent Psychiatry, University of Szeged, Hungary
  • Ildiko Baji
    Department of Child and Adolescent Psychiatry, University of Szeged, Hungary
  • Ágnes Vetró
    Department of Child and Adolescent Psychiatry, University of Szeged, Hungary
  • Krisztina Kapornai
    Department of Child and Adolescent Psychiatry, University of Szeged, Hungary

説明

<jats:p> Although hedonic capacity is diminished during clinical depression, it is unclear whether that deficit constitutes a risk factor or persists after depression episodes remit. To examine these issues, adolescents with current/past major depression (probands; n = 218), never-depressed biological siblings of probands ( n = 207), and emotionally well controls ( n = 183) were exposed to several positively valenced probes. Across baseline and hedonic probe conditions, controls consistently reported higher levels of positive affect than high-risk siblings, and siblings reported higher levels of positive affect than probands (remitted and depressed probands’ reports were similar). Extent of positive affect across the protocol predicted adolescents’ self-reports of social support network and parental reports of offspring’s use of various adaptive mood repair responses in daily life. Attenuated hedonic responding among youths remitted from depression offers partial support for anhedonia as a trait, whereas its presence among never-depressed high-risk siblings argues for anhedonia as a potential diathesis for clinical depression. </jats:p>

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