Association Between Neutrophil to Lymphocyte Ratio and Severity of Coronary Artery Disease
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- Hasan Kaya
- Department of Cardiology, Dicle University Faculty of Medicine, Diyarbakır, Turkey
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- Faruk Ertaş
- Department of Cardiology, Dicle University Faculty of Medicine, Diyarbakır, Turkey
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- Yahya İslamoğlu
- Department of Cardiology, Dicle University Faculty of Medicine, Diyarbakır, Turkey
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- Zekeriya Kaya
- Department of Cardiology, Harran University Faculty of Medicine, Şanlıurfa, Turkey
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- Zuhal Arıtürk Atılgan
- Department of Cardiology, Dicle University Faculty of Medicine, Diyarbakır, Turkey
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- Habib Çil
- Department of Cardiology, Dicle University Faculty of Medicine, Diyarbakır, Turkey
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- Ahmet Çalışkan
- Department of Cardiovascular Surgery, Dicle University Faculty of Medicine, Diyarbakır, Turkey
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- Mesut Aydın
- Department of Cardiology, Dicle University Faculty of Medicine, Diyarbakır, Turkey
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- Mustafa Oylumlu
- Department of Cardiology, Dicle University Faculty of Medicine, Diyarbakır, Turkey
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- Mehmet Serdar Soydinç
- Department of Cardiology, Dicle University Faculty of Medicine, Diyarbakır, Turkey
Description
<jats:p> The aim of this study is to investigate the association between neutrophil to lymphocyte ratio (NLR) and severity of coronary atherosclerosis. A total of 172 patients undergoing coronary angiography were included in the study. Control group consisted of patients with normal coronary arteries. Patients with coronary stenosis were divided into 2 groups by use of Gensini scores. The NLR was higher in severe atherosclerosis group compared with mild atherosclerosis and control groups ( P < .001). In correlation analysis, NLR showed significant correlation with Gensini score. A cutoff value of 2.5 for NLR predicted severe atherosclerosis with a sensitivity and specificity of 62% and 69%, respectively. After multivariate analysis, high levels of NLR were independent predictors of severe atherosclerosis together with glucose and high-density lipoprotein. Our study suggests that the NLR is a predictor of severe atherosclerosis that may be useful for cardiac risk stratification in patients with coronary artery disease. </jats:p>
Journal
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- Clinical and Applied Thrombosis/Hemostasis
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Clinical and Applied Thrombosis/Hemostasis 20 (1), 50-54, 2012-07-11
SAGE Publications
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Details 詳細情報について
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- CRID
- 1360855569416486912
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- ISSN
- 19382723
- 10760296
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- Data Source
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- Crossref