ELECTRON-OPAQUE BODIES AND FAT DROPLETS IN MOUSE LIVER AFTER FASTING OR GLUCOSE INJECTION
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- Nancy L. Trotter
- From the Department of Anatomy, the College of Physicians & Surgeons of Columbia University, New York 10032
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説明
<jats:p>Fasting produces an increased mobilization of lipid from adipose tissue to the liver and a decreased hepatic lipogenesis, but the administration of glucose stimulates lipid synthesis by the liver. After fasting of C3H mice numerous electron-opaque bodies and large lipid droplets were present in the liver. In the liver of untreated controls only a few small electron-opaque bodies and an occasional fat droplet were observed. After glucose injection the number of electron-opaque bodies in the liver was no greater than that observed in livers of saline-injected controls. In the livers of all groups these bodies were located intracellularly within cytoplasmic vesicles; those in extracellular locations were not membrane bounded and were located at indented and thickened hepatocyte plasma membranes or within the space of Disse. In fasted liver the dense bodies were often associated with large fat droplets.</jats:p>
収録刊行物
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- The Journal of Cell Biology
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The Journal of Cell Biology 34 (3), 703-711, 1967-09-01
Rockefeller University Press
