Thiophene-Based Diamidine Forms a “Super” AT Binding Minor Groove Agent

  • Sirish Mallena
    Contribution from the Department of Chemistry, Georgia State University, P.O. Box 4098, Atlanta, Georgia 30302-4098, INSERM U-524 et Laboratoire de Pharmacologie Antitumorale du Centre Oscar Lambret, IRCL, Place de Verdun, 59045 Lille, France, and Cancer Research UK Biomolecular Structure Group, The School of Pharmacy, University of London, London WC1N 1AX, United Kingdom
  • Michael P. H. Lee
    Contribution from the Department of Chemistry, Georgia State University, P.O. Box 4098, Atlanta, Georgia 30302-4098, INSERM U-524 et Laboratoire de Pharmacologie Antitumorale du Centre Oscar Lambret, IRCL, Place de Verdun, 59045 Lille, France, and Cancer Research UK Biomolecular Structure Group, The School of Pharmacy, University of London, London WC1N 1AX, United Kingdom
  • Christian Bailly
    Contribution from the Department of Chemistry, Georgia State University, P.O. Box 4098, Atlanta, Georgia 30302-4098, INSERM U-524 et Laboratoire de Pharmacologie Antitumorale du Centre Oscar Lambret, IRCL, Place de Verdun, 59045 Lille, France, and Cancer Research UK Biomolecular Structure Group, The School of Pharmacy, University of London, London WC1N 1AX, United Kingdom
  • Stephen Neidle
    Contribution from the Department of Chemistry, Georgia State University, P.O. Box 4098, Atlanta, Georgia 30302-4098, INSERM U-524 et Laboratoire de Pharmacologie Antitumorale du Centre Oscar Lambret, IRCL, Place de Verdun, 59045 Lille, France, and Cancer Research UK Biomolecular Structure Group, The School of Pharmacy, University of London, London WC1N 1AX, United Kingdom
  • Arvind Kumar
    Contribution from the Department of Chemistry, Georgia State University, P.O. Box 4098, Atlanta, Georgia 30302-4098, INSERM U-524 et Laboratoire de Pharmacologie Antitumorale du Centre Oscar Lambret, IRCL, Place de Verdun, 59045 Lille, France, and Cancer Research UK Biomolecular Structure Group, The School of Pharmacy, University of London, London WC1N 1AX, United Kingdom
  • David W. Boykin
    Contribution from the Department of Chemistry, Georgia State University, P.O. Box 4098, Atlanta, Georgia 30302-4098, INSERM U-524 et Laboratoire de Pharmacologie Antitumorale du Centre Oscar Lambret, IRCL, Place de Verdun, 59045 Lille, France, and Cancer Research UK Biomolecular Structure Group, The School of Pharmacy, University of London, London WC1N 1AX, United Kingdom
  • W. David Wilson
    Contribution from the Department of Chemistry, Georgia State University, P.O. Box 4098, Atlanta, Georgia 30302-4098, INSERM U-524 et Laboratoire de Pharmacologie Antitumorale du Centre Oscar Lambret, IRCL, Place de Verdun, 59045 Lille, France, and Cancer Research UK Biomolecular Structure Group, The School of Pharmacy, University of London, London WC1N 1AX, United Kingdom

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