Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations

DOI PDF 被引用文献1件
  • Sachiko Yoneyama
    Gillings School of Global Public Health,
  • Yiran Guo
    Center for Applied Genomics, Children's Hospital of Philadelphia, 3615 Civic Center Boulevard, Abramson Research Center, Philadelphia, PA 19104, USA
  • Matthew B. Lanktree
    Department of Medicine
  • Michael R. Barnes
    National Institute for Health Biomedical Research Unit,
  • Clara C. Elbers
    Julius Center for Health Sciences and Primary Care, UMC Utrecht, PO Box 85500, 3508 GA, Utrecht, The Netherlands
  • Konrad J Karczewski
    Stanford University School of Medicine, Stanford, CA 94305, USA
  • Sandosh Padmanabhan
    Institute of Cardiovascular and Medical Sciences,
  • Florianne Bauer
    Julius Center for Health Sciences and Primary Care, UMC Utrecht, PO Box 85500, 3508 GA, Utrecht, The Netherlands
  • Jens Baumert
    Institute of Epidemiology II,
  • Amber Beitelshees
    Division of Endocrinology, Diabetes and Nutrition,
  • Gerald S. Berenson
    Department of Epidemiology, Tulane University, New Orleans, LA 70112, USA
  • Jolanda M.A. Boer
    Center for N utrition, Prevention and Health Services, National Institute for Public Health and the Environment, 3720 BA Bilthoven, The Netherlands
  • Gregory Burke
    Division of Public Health Sciences,
  • Brian Cade
    Division of Sleep Medicine, Harvard Medical School, Boston, MA 02115, USA
  • Wei Chen
    Department of Epidemiology, Tulane University, New Orleans, LA 70112, USA
  • Rhonda M. Cooper-Dehoff
    Department of Pharmacotherapy and Translational Research,
  • Tom R. Gaunt
    MRC Integrative Epidemiology Unit, School of Social and Community Medicine, Bristol BS8 2BN, UK
  • Christian Gieger
    Institute of Genetic Epidemiology,
  • Yan Gong
    Department of Pharmacotherapy and Translational Research,
  • Mathias Gorski
    Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, 93053 Regensburg, Germany
  • Nancy Heard-Costa
    Department of Neurology,
  • Toby Johnson
    Clinical Pharmacology and The Genome Centre, William Harvey Research Institute, Barts,
  • Michael J. Lamonte
    Department of Social and Preventive Medicine, SUNY-Buffalo School of Public Health and Health Professions, Buffalo, NY 14214, USA
  • Caitrin Mcdonough
    Department of Pharmacotherapy and Translational Research,
  • Keri L. Monda
    Gillings School of Global Public Health,
  • N. Charlotte Onland-Moret
    Julius Center for Health Sciences and Primary Care, UMC Utrecht, PO Box 85500, 3508 GA, Utrecht, The Netherlands
  • Christopher P. Nelson
    Department of Cardiovascular Science, University of Leicester, Leicester LE3 9QP, UK
  • Jeffrey R. O'Connell
    Department of Medicine,
  • Jose Ordovas
    Nutrition and Genomics Laboratory, Tufts University, Boston, MA 02111, USA
  • Inga Peter
    Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA
  • Annette Peters
    Institute of Epidemiology II,
  • Jonathan Shaffer
    Division of General Medicine, Center for Behavioral Cardiovascular Health, Columbia University Medical Center, New York, NY 10032, USA
  • Haiqinq Shen
    Department of Medicine,
  • Erin Smith
    Department of Pediatrics and Rady's Children's Hospital, University of California at San Diego, School of Medicine, La Jolla, CA 92093, USA
  • Liz Speilotes
    Division of Gastroenterology, Massachusetts General Hospital, Boston, MA 02114, USA
  • Fridtjof Thomas
    Department of Preventive Medicine, University of Tennessee Health Science Center, Memphis, TN 38163, USA
  • Barbara Thorand
    Institute of Epidemiology II,
  • W. M. Monique Verschuren
    Center for N utrition, Prevention and Health Services, National Institute for Public Health and the Environment, 3720 BA Bilthoven, The Netherlands
  • Sonia S. Anand
    Population Health Research Institute, Hamilton Health Sciences, Department of Medicine, and
  • Anna Dominiczak
    College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK
  • Karina W. Davidson
    Division of General Medicine, Center for Behavioral Cardiovascular Health, Columbia University Medical Center, New York, NY 10032, USA
  • Robert A. Hegele
    Robarts Research Institute, Schulich School of Medicine & Dentistry, University of Western Ontario, London, ON, CanadaN6A 5C1
  • Iris Heid
    Institute of Genetic Epidemiology,
  • Marten H. Hofker
    Department of Molecular Genetics, University Medical Center Groningen, Groningen University, 9700 AB Groningen, The Netherlands
  • Gordon S. Huggins
    Center for Translational Genomics, Molecular Cardiology Research Institute, Tufts Medical Center, Boston, MA 02111, USA
  • Thomas Illig
    Research Unit for Molecular Epidemiology, Helmholtz Zentrum München, German Research Centre for Environmental Health, 85764 Neuherberg, Germany
  • Julie A. Johnson
    Department of Pharmacotherapy and Translational Research,
  • Susan Kirkland
    Department of Community Health & Epidemiology, Dalhousie University, Halifax, NS, Canada
  • Wolfgang König
    Department of Internal Medicine II, Cardiology, University of Ulm Medical Center, Ulm 89081, Germany
  • Taimour Y. Langaee
    Department of Pharmacotherapy and Translational Research,
  • Jeanne Mccaffery
    Weight Control and Diabetes Research Center, The Miriam Hospital and
  • Olle Melander
    Department of Clinical Sciences, Hypertension & Cardiovascular Disease, Lund University, SE 20502 Malmo, Sweden
  • Braxton D. Mitchell
    Division of Endocrinology, Diabetes and Nutrition,
  • Patricia Munroe
    Clinical Pharmacology and The Genome Centre, William Harvey Research Institute, Barts,
  • Sarah S. Murray
    The Scripps Research Institute, Scripps Health, La Jolla, CA 92037, USA
  • George Papanicolaou
    Division of Prevention and Population Sciences, NHLBI, NIH, Bethesda, MD 20824, USA
  • Susan Redline
    Division of Sleep Medicine, Harvard Medical School, Boston, MA 02115, USA
  • Muredach Reilly
    Cardiovascular Institute, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
  • Nilesh J. Samani
    Department of Cardiovascular Science, University of Leicester, Leicester LE3 9QP, UK
  • Nicholas J. Schork
    The Scripps Research Institute, Scripps Health, La Jolla, CA 92037, USA
  • Yvonne T. Van Der Schouw
    Julius Center for Health Sciences and Primary Care, UMC Utrecht, PO Box 85500, 3508 GA, Utrecht, The Netherlands
  • Daichi Shimbo
    Division of General Medicine, Center for Behavioral Cardiovascular Health, Columbia University Medical Center, New York, NY 10032, USA
  • Alan R. Shuldiner
    Department of Medicine and Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
  • Martin D. Tobin
    Department of Health Sciences,
  • Cisca Wijmenga
    Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen 9700 RB, The Netherlands
  • Salim Yusuf
    Population Health Research Institute, Hamilton Health Sciences, Department of Medicine, and
  • Hakon Hakonarson
    Center for Applied Genomics, Children's Hospital of Philadelphia, 3615 Civic Center Boulevard, Abramson Research Center, Philadelphia, PA 19104, USA
  • Leslie A. Lange
    Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
  • Ellen W Demerath
    Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN 55454, USA
  • Caroline S. Fox
    Framingham Heart Study, Boston University School of Medicine, Boston, MA 02118, USA
  • Kari E North
    Gillings School of Global Public Health,
  • Alex P. Reiner
    Department of Epidemiology, University of Washington School of Public Health, Seattle, WA 98195, USA
  • Brendan Keating
    Center for Applied Genomics, Children's Hospital of Philadelphia, 3615 Civic Center Boulevard, Abramson Research Center, Philadelphia, PA 19104, USA
  • Kira C. Taylor
    Department of Epidemiology and Population Health, School of Public Health and Information Sciences, University of Louisville, Louisville, KY 40202, USA

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