Multimodal Actions of Neural Stem Cells in a Mouse Model of ALS: A Meta-Analysis

  • Yang D. Teng
    Departments of Neurosurgery and PM&R, Brigham & Women’s Hospital, Spaulding Rehabilitation Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • Susanna C. Benn
    Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
  • Steven N. Kalkanis
    Departments of Neurosurgery and PM&R, Brigham & Women’s Hospital, Spaulding Rehabilitation Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • Jeremy M. Shefner
    Department of Neurology, State University of New York, Syracuse, NY 13210, USA.
  • Renna C. Onario
    Departments of Neurosurgery and PM&R, Brigham & Women’s Hospital, Spaulding Rehabilitation Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • Bin Cheng
    Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY 10032, USA.
  • Mahesh B. Lachyankar
    Department of Neurology, Boston Children’s Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Michael Marconi
    Department of Neurology, Boston Children’s Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Jianxue Li
    Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
  • Dou Yu
    Departments of Neurosurgery and PM&R, Brigham & Women’s Hospital, Spaulding Rehabilitation Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • Inbo Han
    Departments of Neurosurgery and PM&R, Brigham & Women’s Hospital, Spaulding Rehabilitation Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • Nicholas J. Maragakis
    Department of Neurology, Johns Hopkins University, Baltimore, MD 21287, USA.
  • Jeronia Lládo
    Department of Neurology, Johns Hopkins University, Baltimore, MD 21287, USA.
  • Kadir Erkmen
    Departments of Neurosurgery and PM&R, Brigham & Women’s Hospital, Spaulding Rehabilitation Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • D. Eugene Redmond
    Department of Psychiatry and Neurosurgery, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Richard L. Sidman
    Departments of Neurosurgery and PM&R, Brigham & Women’s Hospital, Spaulding Rehabilitation Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • Serge Przedborski
    Movement Disorder Division, Neurological Institute, Center for Neurobiology and Behavior, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.
  • Jeffrey D. Rothstein
    Department of Neurology, Johns Hopkins University, Baltimore, MD 21287, USA.
  • Robert H. Brown
    Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
  • Evan Y. Snyder
    Departments of Neurosurgery and PM&R, Brigham & Women’s Hospital, Spaulding Rehabilitation Hospital and Harvard Medical School, Boston, MA 02115, USA.

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説明

<jats:p> A meta-analysis reports the beneficial effects of transplanting mouse or human neural stem cells into the spinal cord of the SOD1 <jats:sup>G93A</jats:sup> mouse, a model of ALS. </jats:p>

収録刊行物

  • Science Translational Medicine

    Science Translational Medicine 4 (165), 165ra164-, 2012-12-19

    American Association for the Advancement of Science (AAAS)

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