<i>Neisseria gonorrhoeae</i> II. Colonial Variation and Pathogenicity During 35 Months In Vitro

DOI Web Site 2 Citations
  • Douglas S. Kellogg
    Venereal Disease Research Laboratory, National Communicable Disease Center, Atlanta, Georgia 30333
  • Irun R. Cohen
    Venereal Disease Research Laboratory, National Communicable Disease Center, Atlanta, Georgia 30333
  • Leslie C. Norins
    Venereal Disease Research Laboratory, National Communicable Disease Center, Atlanta, Georgia 30333
  • Arnold L. Schroeter
    Venereal Disease Research Laboratory, National Communicable Disease Center, Atlanta, Georgia 30333
  • Gilbert Reising
    Venereal Disease Research Laboratory, National Communicable Disease Center, Atlanta, Georgia 30333

Abstract

<jats:p> During 35 months of selective in vitro cultivation, <jats:italic>Neisseria gonorrhoeae</jats:italic> cells retained their virulence for humans and were shown to be closely related to a particular colonial morphology. Saline-autoagglutinability was the only other characteristic distinguishing virulent from avirulent cells. Human responses to challenge with cells of the different colonial types were studied for their relationships to virulence or avirulence. </jats:p>

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